TOX3
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Official Full Name
TOX high mobility group box family member 3 -
Overview
The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
TOX3;TOX high mobility group box family member 3;TNRC9, trinucleotide repeat containing 9;CAGF9;trinucleotide repeat containing 9;trinucleotide repeat-containing gene 9 protein;CAG trinucleotide repeat-containing gene F9 protein;TNRC9
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TOX3-17244M | Recombinant Mouse TOX3 Protein | Mammalian Cells | Mouse | His |
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| TOX3-4733C | Recombinant Chicken TOX3 | Mammalian Cells | Chicken | His |
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| TOX3-4734C | Recombinant Chicken TOX3 | Mammalian Cells | Chicken | His |
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| TOX3-9527M | Recombinant Mouse TOX3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TOX3-9527M-B | Recombinant Mouse TOX3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TOX3 involved in several pathways and played different roles in them. We selected most pathways TOX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TOX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TOX3 has several biochemical functions, for example, DNA binding,chromatin binding,estrogen response element binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TOX3 itself. We selected most functions TOX3 had, and list some proteins which have the same functions with TOX3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | MSXC,HMBOX1,HOXB1,ZNF596,IRX1B,NKX2.5,EHF,DBX1B,MXTX1,KIF4 |
| protein homodimerization activity | SDCBP2,PVRL3B,E2F8,DGAT2,VPS25,UGT1A1,TG,ASGR1,HOMER2,PAFAH1B1 |
| chromatin binding | CNBPA,TRPS1,JARID2B,CBFA2T3,POLD1,NKX2,DLX2,MEIS3,MCMBP,HMGXB4A |
| phosphoprotein binding | FKBP4,CACNB2,DPYS,PKD2,CBX4,SNCA,DPYSL3,PITX2,URI1,LRP11 |
| estrogen response element binding | TRIM24,ESR1,ESR2 |
Interacting Protein
TOX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TOX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TOX3.
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