TOM1

  • Official Full Name

    target of myb1 (chicken)
  • Overview

    This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    TOM1;target of myb1 (chicken);target of myb1 (chicken) homolog;target of Myb protein 1;target of myb 1;FLJ33404

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Chicken
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • GST
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
TOM1-3344H Recombinant Human TOM1, His-tagged E.coli Human His 140-493aa
TOM1-150H Recombinant Human TOM1, GST-tagged E.coli Human GST 1-493 a.a.
TOM1-4889R Recombinant Rhesus monkey TOM1 Protein, His-tagged Mammalian Cells Rhesus macaque His
TOM1-6701C Recombinant Chicken TOM1 Mammalian Cells Chicken His
TOM1-1807HCL Recombinant Human TOM1 cell lysate Human Non
TOM1-2308H Recombinant Human TOM1 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
TOM1-4703R Recombinant Rhesus Macaque TOM1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
TOM1-4703R-B Recombinant Rhesus Macaque TOM1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque

    Involved Pathway

    TOM1 involved in several pathways and played different roles in them. We selected most pathways TOM1 participated on our site, such as C-MYB transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with TOM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    C-MYB transcription factor network PTCRA,CEBPB,CEBPA,PIAS3,MYF6,SKI,SLC25A3,CLTA,CDKN1B,TRIM28

    Protein Function

    TOM1 has several biochemical functions, for example, clathrin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TOM1 itself. We selected most functions TOM1 had, and list some proteins which have the same functions with TOM1. You can find most of the proteins on our site.

    Function Related Protein
    clathrin binding SYT1A,NCALD,SYT5A,SCLT1,SMAP1,SYT3,SYT11A,SYT5B,PICALM,SYT11B
    protein binding C16orf79,DAPK2,DDX19A,MMP15,USH1C,MYO5A,C10orf28,ZNF18,TAGLN2,TGFB3

    Interacting Protein

    TOM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TOM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TOM1.

    UBB;TOLLIP;ZFYVE16;TOLLIP;Map3k1;TOM1L1

    Resources

    References

    • Nishikiori, M; Mori, M; et al. A Host Small GTP-binding Protein ARL8 Plays Crucial Roles in Tobamovirus RNA Replication. PLOS PATHOGENS 7:-(2011).
    • De, M; Abazeed, ME; et al. Direct binding of the Kex2p cytosolic tail to the VHS domain of yeast Gga2p facilitates TGN to prevacuolar compartment transport and is regulated by phosphorylation. MOLECULAR BIOLOGY OF THE CELL 24:495-509(2013).

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