TOB1

  • Official Full Name

    transducer of ERBB2, 1

  • Overview

    This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants.

  • Synonyms

    TOB1;transducer of ERBB2, 1;TROB1;protein Tob1;TOB;TROB;transducer of erbB-2 1;proliferation-inducing gene 49;APRO6;PIG49;MGC34446;MGC104792
Cat.# Product name Source (Host) Species Tag Protein Length Price
TOB1-1110C Recombinant Chicken TOB1 Mammalian Cells Chicken His
TOB1-875HCL Recombinant Human TOB1 293 Cell Lysate HEK293 Human Non

    Involved Pathway

    TOB1 involved in several pathways and played different roles in them. We selected most pathways TOB1 participated on our site, such as BMP signalling and regulation,Diurnally regulated genes with circadian orthologs,RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TOB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    BMP signalling and regulation NOG
    RNA degradation PABPC4,TOB2,PABPC3,CNOT3,HSPA9,SMX5,CNOT10,DCP1B,BTG2,CNOT2
    Diurnally regulated genes with circadian orthologs ZFR,RBPMS,CBX3,EIF4G2,STBD1,QK,CRY1,MYF6,CEBPB,NR1D2

    Protein Function

    TOB1 has several biochemical functions, for example, SH3/SH2 adaptor activity,SMAD binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TOB1 itself. We selected most functions TOB1 had, and list some proteins which have the same functions with TOB1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CCDC36,RNF6,PRPF19,CREBZF,HEY1,GAGE2D,ZFP932,ORAI2,ERGIC2,JAKMIP2
    SMAD binding ACVR1B,TGFBR3,RNF111,CREBBP,EID2,SKOR1B,SNW1,FKBP1A,SOD3,COL3A1
    SH3/SH2 adaptor activity STAM,SH2D1A,SH3BGR,SH2D2A,SOCS2,SH3BGRL,GRB14,HSH2D,SLA,CRK
    receptor tyrosine kinase binding GNB2L1,ANGPT4,TRP53,PTPN1,ARHGEF16,TP53,NRG3,DOCK4,PTPN2,NRG1
    transcription corepressor activity JUNB,ZEB1,LMCD1,NSD1,CITED2,FOXP3,HDAC4,CIR1,SSX4,MTA1

    Interacting Protein

    TOB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TOB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TOB1.

    CNOT7;CPEB3;CNOT1;PABPC1

    Resources

    Research Area

    Phospholipases, Small GTPases, and Other Molecules in the Akt Pathway

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All TOB1 Products

    Required fields are marked with *

    My Review for All TOB1 Products

    Required fields are marked with *