TNPO3
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Official Full Name
transportin 3 -
Overview
The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010] -
Synonyms
TNPO3;transportin 3;IPO12;TRNSR;LGMD1F;MTR10A;TRN-SR;TRN-SR2;transportin-3;imp12;importin 12;transportin-SR;limb girdle muscular dystrophy 1F (autosomal dominant)
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TNPO3-3338H | Recombinant Human TNPO3, GST-tagged | E.coli | Human | GST | C-term-350aa | |
| TNPO3-11310Z | Recombinant Zebrafish TNPO3 | Mammalian Cells | Zebrafish | His |
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| TNPO3-17205M | Recombinant Mouse TNPO3 Protein | Mammalian Cells | Mouse | His |
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| TNPO3-31582TH | Recombinant Human TNPO3 | Wheat Germ | Human | Non | 255 amino acids |
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| TNPO3-4884R | Recombinant Rhesus monkey TNPO3 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| TNPO3-4698R | Recombinant Rhesus Macaque TNPO3 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| TNPO3-4698R-B | Recombinant Rhesus Macaque TNPO3 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| TNPO3-9504M | Recombinant Mouse TNPO3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TNPO3-9504M-B | Recombinant Mouse TNPO3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TNPO3 involved in several pathways and played different roles in them. We selected most pathways TNPO3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TNPO3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TNPO3 has several biochemical functions, for example, identical protein binding,nuclear localization sequence binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNPO3 itself. We selected most functions TNPO3 had, and list some proteins which have the same functions with TNPO3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nuclear localization sequence binding | IPO5,KPNA6,KPNA5,RANBP6,KPNA4,IPO4,TNPO1,KPNA1,TNPO2,KPNA3 |
| identical protein binding | KCNRG,CEP170L,VPS4B,TLE1,SHANK3,CLDN16,MYD88,PTEN,PTPRG,USP4 |
| protein binding | PRDM5,KSR1,MPP2,EIF3H,KIAA1199,HSD17B10,NLGN4X,TBC1D10A,IKBKB,ILVBL |
| receptor activity | RAMP3,LILRA3,KLRB1B,LILRB3,GRIK3,NLGN3A,OGFRL2,NLGN4Y,PVRL2L,PAQR3A |
| protein transporter activity | TNPO1,RAB4A,CHMP7,IPO5,AP2B1,KPNB1,VPS26A,XPO5,AP3S1,KPNB3 |
Interacting Protein
TNPO3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNPO3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNPO3.
gag-pol;PTP4A3;USP19;MYC;C20orf24;BRF2;NEK6;PHLDA3;UBE2S;SMURF2;Ppp2r3a;Junb
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