TMPRSS6
-
Official Full Name
transmembrane protease, serine 6 -
Overview
The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] -
Synonyms
TMPRSS6;transmembrane protease, serine 6;IRIDA;transmembrane protease serine 6;matriptase-2;type II transmembrane serine protease 6;membrane-bound mosaic serine proteinase matriptase-2
Recombinant Proteins
- Human
- Mouse
- Wheat Germ
- Insect Cells
- HEK293
- Mammalian Cells
- E.coli
- GST
- Flag
- His&Myc
- Non
- His&GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TMPRSS6-126H | Recombinant Human TMPRSS6 protein, GST-tagged | Wheat Germ | Human | GST | 1 a.a. - 461 a.a. |
|
| TMPRSS6-127H | Recombinant Human TMPRSS6 protein, DDK-tagged | Insect Cells | Human | Flag | 77-811aa |
|
| TMPRSS6-17123M | Recombinant Mouse TMPRSS6, His-MYC-tagged | HEK293 | Mouse | His&Myc | 81-881 a.a. |
|
| TMPRSS6-1799HCL | Recombinant Human TMPRSS6 cell lysate | Human | Non |
|
||
| TMPRSS6-2746M | Recombinant Mouse TMPRSS6 Protein (81-811 aa), His-Myc-tagged | Insect Cells | Mouse | His&Myc | 81-811 aa |
|
| TMPRSS6-3247HFL | Recombinant Full Length Human TMPRSS6 protein, Flag-tagged | Mammalian Cells | Human | Flag | Full L. |
|
| TMPRSS6-430H | Recombinant Human TMPRSS6 Protein, His&GST-tagged | E.coli | Human | His&GST | Ala608-Thr811 |
|
Involved Pathway
TMPRSS6 involved in several pathways and played different roles in them. We selected most pathways TMPRSS6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TMPRSS6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TMPRSS6 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TMPRSS6 itself. We selected most functions TMPRSS6 had, and list some proteins which have the same functions with TMPRSS6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | FKBP10B,ATP2A1,CALB1,RASGRP4,SLC25A23B,NKD1,CETN3,TPO,MATN3A,PCDH2AB9 |
Interacting Protein
TMPRSS6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMPRSS6 here. Most of them are supplied by our site. Hope this information will be useful for your research of TMPRSS6.
Resources
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References
- Canavese, C; Quaglia, M; et al. Very high frequency of TMPRSS6 gene variations in iron deficiency anaemia of patients with polyendocrine autoimmune syndromes: more than a casual association?. BRITISH JOURNAL OF HAEMATOLOGY 161:147-150(2013).
- Chen, WJ; Sun, CC; et al. A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum. HAEMATOLOGICA 98:296-304(2013).
