TMED2
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Official Full Name
transmembrane emp24 domain trafficking protein 2 -
Overview
Transmembrane emp24 domain-containing protein 2 is a protein that in humans is encoded by the TMED2 gene. -
Synonyms
TMED2;transmembrane emp24 domain trafficking protein 2;transmembrane emp24 domain-containing protein 2;P24A;RNP24;p24beta1;membrane protein p24A;p24 family protein beta-1;coated vesicle membrane protein;p24;FLJ21323
Recombinant Proteins
- Human
- Cynomolgus
- Chicken
- Rat
- Zebrafish
- Cricetulus griseus
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
TMED2 involved in several pathways and played different roles in them. We selected most pathways TMED2 participated on our site, such as Asparagine N-linked glycosylation,COPII (Coat Protein 2) Mediated Vesicle Transport,Cargo concentration in the ER, which may be useful for your reference. Also, other proteins which involved in the same pathway with TMED2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Post-translational protein modification | GALNTL2,SCFD1,ARSI,MUC15,SCMH1,CBX4,SSPO,THSD7A,ATPBD4,RING1 |
| Membrane Trafficking | CPD,NECAP1,COPZ1,GJB4,EXOC6,CX30.3,SNX9,BLOC1S3,COPE,TBC1D8B |
| ER to Golgi Anterograde Transport | GORASP1,SCFD1,TFG,TRAPPC6BL,TRAPPC2L,CNIH3,SERPINA1L,SEC23IP,TRAPPC6B,NAPB |
| Pre-NOTCH Expression and Processing | RAB6A |
| Cargo concentration in the ER | PREB,SEC23A,MCFD2,CNIH3,SEC24A,SERPINA1L,AREG,CTSC,LMAN2L,CNIH |
| Metabolism of proteins | IGFBP5,SENP5,IGFBP4,PMPCB,IGFALS,BCHE,PAPPA,MPDU1A,PHC3,CNIH2 |
| COPII (Coat Protein 2) Mediated Vesicle Transport | GOLGA2,CTSC,TRAPPC2L,YKT6,TRAPPC6BL,TMED10,LMAN2L,MCFD2,USO1,TRAPPC4 |
| Asparagine N-linked glycosylation | MGAT4A,ST8SIA2,OS9,PPP6C,NAPAA,SLC35A1,TRAPPC4,MCFD2,TRAPPC6BL,NEU3 |
Protein Function
TMED2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TMED2 itself. We selected most functions TMED2 had, and list some proteins which have the same functions with TMED2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CIRH1A,NR1H4,NCK1,ZNF502,ABI2,NPHP1,DHRS1,RAD23B,GYG1,JAG1 |
Interacting Protein
TMED2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMED2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TMED2.
TMED10;F2RL1;CD59;SURF4
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References
- Sakakibara, M; Uenoyama, Y; et al. Microarray Analysis of Perinatal-Estrogen-Induced Changes in Gene Expression Related to Brain Sexual Differentiation in Mice. PLOS ONE 8:-(2013).
- Hou, WY; Sarikaya, D; et al. IS TMED2 ESSENTIAL IN THE CHORION FOR NORMAL INTERACTION BETWEEN THE ALLANTOIS AND THE CHORION IN MICE?. PLACENTA 34:A84-A84(2013).
