TMC1
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Official Full Name
transmembrane channel-like 1 -
Overview
This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, it is known to be required for normal function of cochlear hair cells. Mutations in this gene have been associated with progressive postlingual hearing loss and profound prelingual deafness. -
Synonyms
TMC1;transmembrane channel-like 1;DFNA36, DFNB7, DFNB11, transmembrane, cochlear expressed, 1;transmembrane channel-like protein 1;4933416G09Rik;Beethoven protein;Bth;CWEA1;Deafness autosomal dominant 36;Deafness autosomal recessive 11;Deafness autosomal recessive 7;Deafness protein;DFNA36;DFNB11;DFNB7;dn;Transmembrane channel like protein 1;Transmembrane cochlear expressed protein 1;OTTHUMP00000021473;transmembrane, cochlear expressed, 1;transmembrane cochlear-expressed protein 1
Recombinant Proteins
- Mouse
- Chicken
- Human
- Mus musculus
- Mammalian Cells
- E.coli
- HEK293
- His
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TMC1-16855M | Recombinant Mouse TMC1 Protein | Mammalian Cells | Mouse | His |
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| TMC1-1717C | Recombinant Chicken TMC1 | Mammalian Cells | Chicken | His |
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| RFL35471HF | Recombinant Full Length Human Transmembrane Channel-Like Protein 1(Tmc1) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-760) |
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| RFL9917MF | Recombinant Full Length Mouse Transmembrane Channel-Like Protein 1(Tmc1) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-757aa) |
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| Tmc1-0284M | Recombinant Mouse Tmc1 Full Length Transmembrane protein, His-tagged | E.coli | Mouse | His | Full L. 1-757aa |
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| TMC1-9256M | Recombinant Mouse TMC1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| TMC1-9256M-B | Recombinant Mouse TMC1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TMC1 involved in several pathways and played different roles in them. We selected most pathways TMC1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TMC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TMC1 has several biochemical functions, for example, voltage-gated calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TMC1 itself. We selected most functions TMC1 had, and list some proteins which have the same functions with TMC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| voltage-gated calcium channel activity | RYR1,IL1RAPL1,CACNG2B,TPC3,ITGAV,CACNG1,CACNB3A,CACNG7,CACNA2D2,CACNA2D4 |
Interacting Protein
TMC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TMC1.
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