TM7SF2
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Official Full Name
transmembrane 7 superfamily member 2 -
Overview
Delta(14)-sterol reductase is an enzyme that in humans is encoded by the TM7SF2 gene. -
Synonyms
TM7SF2;transmembrane 7 superfamily member 2;delta(14)-sterol reductase;ANG1;DHCR14A;NET47;delta-14-SR;sterol C14-reductase;C-14 sterol reductase;another new gene 1 protein;putative sterol reductase SR-1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TM7SF2-1894Z | Recombinant Zebrafish TM7SF2 | Mammalian Cells | Zebrafish | His |
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| RFL17380BF | Recombinant Full Length Bovine Delta(14)-Sterol Reductase(Tm7Sf2) Protein, His-Tagged | E.coli | Bovine | His | Full L. Full Length (1-418) |
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| RFL2626HF | Recombinant Full Length Human Delta(14)-Sterol Reductase(Tm7Sf2) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-418) |
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| RFL33324MF | Recombinant Full Length Mouse Delta(14)-Sterol Reductase(Tm7Sf2) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-418) |
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Involved Pathway
TM7SF2 involved in several pathways and played different roles in them. We selected most pathways TM7SF2 participated on our site, such as Steroid biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with TM7SF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | ASL2,LDHC,POLR3D,CHIA.4,AGPAT3,TSTA3,ADSS,ST3GAL4,CDA,HPDB |
| Steroid biosynthesis | EBP,SOAT1,CYP2R1,HSD17B7,LSS,SC4MOL,Cel,MSMO1,CELL,DHCR7 |
Protein Function
TM7SF2 has several biochemical functions, for example, oxidoreductase activity, acting on the CH-CH group of donors,oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor. Some of the functions are cooperated with other proteins, some of the functions could acted by TM7SF2 itself. We selected most functions TM7SF2 had, and list some proteins which have the same functions with TM7SF2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| oxidoreductase activity, acting on the CH-CH group of donors | SRD5A3,DPYDB,GCDHA,SRD5A2A,TECRL,PPP1R2,GCDHB,TECRB,TECRL2B,COX15 |
| oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | DHCR24,BDH2,LBR,SRD5A3 |
Interacting Protein
TM7SF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TM7SF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TM7SF2.
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References
- Gao, JL; Xia, LB; et al. TM7SF1 (GPR137B): a novel lysosome integral membrane protein. MOLECULAR BIOLOGY REPORTS 39:8883-8889(2012).
- Traggiai, E; Lunardi, C; et al. Generation of anti-NAG-2 mAb from patients' memory B cells: implications for a novel therapeutic strategy in systemic sclerosis. INTERNATIONAL IMMUNOLOGY 22:367-374(2010).
