TM2D2
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Official Full Name
TM2 domain containing 2 -
Overview
The protein encoded by this gene contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily. This protein has sequence and structural similarities to the beta-amyloid binding protein (BBP), but, unlike BBP, it does not regulate a response to beta-amyloid peptide. This protein may have regulatory roles in cell death or proliferation signal cascades. This gene has multiple alternatively spliced transcript variants which encode two different isoforms. -
Synonyms
TM2D2;TM2 domain containing 2;TM2 domain-containing protein 2;BLP1;BBP-like protein 1;Beta-amyloid-binding protein-like protein 1;TM2D2_HUMAN;TM2 domain containing 2, isoform a
Recombinant Proteins
- Mouse
- Rhesus macaque
- Rat
- Zebrafish
- Human
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- Bovine
- Mus musculus
- Xenopus laevis
- zebrafish
- Pongo Abelii
- Mammalian Cells
- HEK293
- E.coli
- His
- Non
- His&Fc&Avi
Involved Pathway
TM2D2 involved in several pathways and played different roles in them. We selected most pathways TM2D2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TM2D2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TM2D2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TM2D2 itself. We selected most functions TM2D2 had, and list some proteins which have the same functions with TM2D2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
TM2D2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TM2D2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TM2D2.
PARP2
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References
- Bukiya, AN; McMillan, J; et al. Activation of Calcium- and Voltage-gated Potassium Channels of Large Conductance by Leukotriene B4. JOURNAL OF BIOLOGICAL CHEMISTRY 289:35314-35325(2014).
- Kuntamallappanavar, G; Toro, L; et al. Both Transmembrane Domains of BK beta 1 Subunits Are Essential to Confer the Normal Phenotype of beta 1-Containing BK Channels. PLOS ONE 9:-(2014).
