TIMM8B
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Official Full Name
translocase of inner mitochondrial membrane 8 homolog B (yeast) -
Overview
This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma. -
Synonyms
TIMM8B;translocase of inner mitochondrial membrane 8 homolog B (yeast);translocase of inner mitochondrial membrane 8 (yeast) homolog B;mitochondrial import inner membrane translocase subunit Tim8 B;DDP2;FLJ21744;MGC102866;MGC117373;TIM8B;Deafness dystonia protein 2;Small zinc finger like protein DDP2;Translocase of inner mitochondrial membrane 8 homolog b;DDP-like protein;OTTHUMP00000221758
Recombinant Proteins
- Mouse
- Rhesus macaque
- Rat
- Zebrafish
- Human
- Mammalian Cells
- HEK293
- E.coli
- His
- Myc&DDK
- His&Fc&Avi
Involved Pathway
TIMM8B involved in several pathways and played different roles in them. We selected most pathways TIMM8B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TIMM8B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TIMM8B has several biochemical functions, for example, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TIMM8B itself. We selected most functions TIMM8B had, and list some proteins which have the same functions with TIMM8B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | SEMG2,MTBL,USP2,CYP2C39,AGMAT,SOBP,ZNF311,NR6A1B,ZBTB12,TPH1B |
Interacting Protein
TIMM8B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TIMM8B here. Most of them are supplied by our site. Hope this information will be useful for your research of TIMM8B.
Atp6v1a
Resources
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References
- Cadinanos, J; Llorente, JL; et al. NOVEL GERMLINE SDHD DELETION ASSOCIATED WITH AN UNUSUAL SYMPATHETIC HEAD AND NECK PARAGANGLIOMA. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK 33:1233-1240(2011).
- Fullston, T; Mitchell, M; et al. Mitochondrial inhibition during preimplantation embryogenesis shifts the transcriptional profile of fetal mouse brain. REPRODUCTION FERTILITY AND DEVELOPMENT 23:691-701(2011).
