TICAM2
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Official Full Name
toll-like receptor adaptor molecule 2 -
Overview
TIRP is a Toll/interleukin-1 receptor (IL1R; MIM 147810) (TIR) domain-containing adaptor protein involved in Toll receptor signaling (see TLR4; MIM 603030). -
Synonyms
TICAM2;toll-like receptor adaptor molecule 2;TIR domain-containing adapter molecule 2;TICAM 2;TIRP;TRAM;cytoplasmic adaptor;TRIF-related adaptor molecule;NF-kappa-B-activating protein 502;toll-like receptor adaptor protein 3;putative NF-kappa-B-
Recombinant Proteins
- Human
- Mouse
- Cynomolgus
- Rhesus macaque
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- GST&His
- Non
- Avi&Fc&His
- DDK&Myc
Involved Pathway
TICAM2 involved in several pathways and played different roles in them. We selected most pathways TICAM2 participated on our site, such as NF-kappa B signaling pathway,Toll-like receptor signaling pathway,Pertussis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TICAM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Toll-like receptor signaling pathway | IKBKB,IFNA16,NFKBIAB,PIK3CA,NFKB1,TRAF6,SPP1,IFNA7,LY96,CD86 |
| NF-kappa B signaling pathway | PLCG1,LY96,IL1R1,ERC1,TRAF2,TRAF1,CCL21,NFKB2,PLAU,TNFSF13B |
| Pertussis | PYCARD,IRAK4,IL12A,LY96,ITGB2,GNAI2,IRF1,MAPK12,IRF8,CASP7 |
| Hepatitis B | IFNA8,STAT4,EGR2,CREB3L3,TGFBR1,NRAS,HBXIP,PIK3CG,TGFB2,IFNA4 |
Protein Function
TICAM2 has several biochemical functions, for example, phospholipid binding,protein binding,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TICAM2 itself. We selected most functions TICAM2 had, and list some proteins which have the same functions with TICAM2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RARG,MTRR,CCDC155,STXBP2,PTPN14,ATP11C,SLC7A1,EIF3J,SKAP1,OLIG3 |
| signal transducer activity | OPRD1A,MUL1,ZDHHC17,DRD2A,MRGPRA5,ADRA1BB,DKKL1,MTNR1AA,TAS2R109,CD24 |
| phospholipid binding | NSFL1C,SNCA,AMPH,NR5A2,BIN2,PLA2G4C,CPS1,NR5A1,OTC,SERPINB1A |
Interacting Protein
TICAM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TICAM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TICAM2.
MEOX2;C;TLR4;IL1R1;TIRAP;TICAM1;IL1RAP;TRAF6;PIAS2;FTH1;Smad6
Resources
Research Area
Apoptosis Adaptor ProteinsAdaptor Proteins
NOD-like Receptors and the Inflammasome
IL-1 Family Signaling Molecules
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References
