TIAM1
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Official Full Name
T-cell lymphoma invasion and metastasis 1 -
Overview
Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. -
Synonyms
TIAM1;T-cell lymphoma invasion and metastasis 1;T-lymphoma invasion and metastasis-inducing protein 1;T cell lymphoma invasion and metastasis 1;T lymphoma invasion and metastasis inducing TIAM1 protein;TIAM-1;TIAM1_HUMAN;OTTHUMP00000107263;human T-lymphoma invasion and metastasis inducing TIAM1 protein
Recombinant Proteins
- Rhesus macaque
- Human
- Mouse
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- His
- His&T7
- Myc&DDK
- Non
- GST
- His&Fc&Avi
Involved Pathway
TIAM1 involved in several pathways and played different roles in them. We selected most pathways TIAM1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TIAM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TIAM1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TIAM1 itself. We selected most functions TIAM1 had, and list some proteins which have the same functions with TIAM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
TIAM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TIAM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TIAM1.
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References
- Gallicchio, MA; Bach, LA; et al. Uptake of advanced glycation end products by proximal tubule epithelial cells via macropinocytosis. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1833:2922-2932(2013).
- Birukova, AA; Tian, YF; et al. VE-cadherin trans-interactions modulate Rac activation and enhancement of lung endothelial barrier by iloprost. JOURNAL OF CELLULAR PHYSIOLOGY 227:3405-3416(2012).
