TGM5
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Official Full Name
transglutaminase 5 -
Overview
This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome. -
Synonyms
TGM5;transglutaminase 5;protein-glutamine gamma-glutamyltransferase 5;TGX;Protein glutamine gamma glutamyltransferase 5;TGase 5;TGase X;TGase5;TGMX;Transglutaminase X;TG(X);TGase-5;transglutaminase V;transglutaminase-5;TGM6;TGASEX
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Mammalian cells
- GST
- His
- Non
- Myc&DDK
- Flag
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TGM5-3211H | Recombinant Human TGM5, GST-tagged | E.coli | Human | GST | C-320aa | |
| TGM5-16718M | Recombinant Mouse TGM5 Protein | Mammalian Cell | Mouse | His |
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| TGM5-1109HCL | Recombinant Human TGM5 293 Cell Lysate | HEK293 | Human | Non |
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| TGM5-1771H | Recombinant Human TGM5 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| TGM5-1869HFL | Recombinant Full Length Human TGM5 Protein, C-Flag-tagged | Mammalian cells | Human | Flag | Full L. |
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| TGM5-2187H | Recombinant Human TGM5 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| TGM5-2187H-B | Recombinant Human TGM5 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| Tgm5-6400M | Recombinant Mouse Tgm5 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| TGM5-9170M | Recombinant Mouse TGM5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TGM5-9170M-B | Recombinant Mouse TGM5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TGM5 involved in several pathways and played different roles in them. We selected most pathways TGM5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TGM5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
TGM5 has several biochemical functions, for example, metal ion binding,protein-glutamine gamma-glutamyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TGM5 itself. We selected most functions TGM5 had, and list some proteins which have the same functions with TGM5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein-glutamine gamma-glutamyltransferase activity | F13A1,TGM2B,TGM4,TGM2A,TGM1,EPB42,F13A1B,TGM2,TGM3,F13A1A.1 |
| metal ion binding | ZNF426,PDE10A,ITGAM,ACAP2,ZMYND17,ZNF521,PLEKHF2,HIC1L,ARHGAP29,LOC780933 |
Interacting Protein
TGM5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TGM5 here. Most of them are supplied by our site. Hope this information will be useful for your research of TGM5.
Resources
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References
- Senapati, S; Gutierrez-Achury, J; et al. Evaluation of European coeliac disease risk variants in a north Indian population. EUROPEAN JOURNAL OF HUMAN GENETICS 23:530-535(2015).
- Salmi, TT; Hervonen, K; et al. Celiac disease evolving into dermatitis herpetiformis in patients adhering to normal or gluten-free diet. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY 50:387-392(2015).
