TFG
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Official Full Name
TRK-fused gene -
Overview
There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. -
Synonyms
TFG;TRK-fused gene;protein TFG;FLJ36137;TF6;OTTHUMP00000214045;OTTHUMP00000214046;OTTHUMP00000214047;OTTHUMP00000214048;TFG_HUMAN;TRK fused;TRK fused gene protein;TRK-fused gene protein;TRKT3;TRKT3 oncogene
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Human
- Mouse
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TFG-10374Z | Recombinant Zebrafish TFG | Mammalian Cell | Zebrafish | His |
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| TFG-4681R | Recombinant Rhesus monkey TFG Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| TFG-1124HCL | Recombinant Human TFG 293 Cell Lysate | HEK293 | Human | Non |
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| TFG-1125HCL | Recombinant Human TFG 293 Cell Lysate | HEK293 | Human | Non |
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| TFG-4497R | Recombinant Rhesus Macaque TFG Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| TFG-4497R-B | Recombinant Rhesus Macaque TFG Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| TFG-5794H | Recombinant Human TFG Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Tfg-6381M | Recombinant Mouse Tfg Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
TFG involved in several pathways and played different roles in them. We selected most pathways TFG participated on our site, such as Asparagine N-linked glycosylation,COPII (Coat Protein 2) Mediated Vesicle Transport,ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with TFG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Post-translational protein modification | NSMCE1,GNE,SCMH1,SCFD1,NSMCE4A,NSMCE2,MUC12,MUC5AC,MPDU1A,ADAMTS13 |
| Asparagine N-linked glycosylation | GOLGA2,ST3GAL3A,DERL2,NANP,SEC23IP,ALG10B,SERPINA1L,NAPG,MPDU1B,NEU3 |
| Thyroid cancer | CDH1,NRAS,HRAS,CCDC6,PAX8,TCF7L2,RXRA,PPARG,NCOA4,CCND1 |
| Pathways in cancer | DAPK2,GNAS,WNT2,Kitl,BCR,MAPK10,PTGS2,MET,PGF,BID |
| Membrane Trafficking | TMED10,GJA4,GOLGA2,EXOC1,PPP6R3,MCFD2,YIPF6,TRAPPC6A,GJD3,HIP1R |
| ER to Golgi Anterograde Transport | MIA3,TRAPPC9,SEC23A,USO1,NAPAB,SEC16B,NAPAA,PPP6R3,NSFA,SCFD1 |
| COPII (Coat Protein 2) Mediated Vesicle Transport | SERPINA1L,CNIH3,CNIH,GORASP1,NSFB,TRAPPC6B,TRAPPC6A,TRAPPC4,SEC23A,TRAPPC10 |
| Metabolism of proteins | TMED10,IGFBP6,ACE,TPP1,DDOST,DDIT3,TRAPPC2,RING1,DDX11,MAGT1 |
Protein Function
TFG has several biochemical functions, for example, protein binding,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TFG itself. We selected most functions TFG had, and list some proteins which have the same functions with TFG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CRY1,EIF5,PRDM14,MED29,DSP,ARNTL,C11orf57,IFT20,CHD2,FAM129A |
| signal transducer activity | GPR124,GPR141,FST,NDFIP1,TAS2R129,GRM6B,OLFR10,GNAO1,NPFFR1L2,VMN1R45 |
Interacting Protein
TFG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFG here. Most of them are supplied by our site. Hope this information will be useful for your research of TFG.
BOLL;VPS37C;CEP55;SEC24A;CSTF2;HNRNPF;EWSR1
Resources
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References
- Guzman, E; Hope, J; et al. Bovine gamma delta T Cells Are a Major Regulatory T Cell Subset. JOURNAL OF IMMUNOLOGY 193:208-222(2014).
- Masuda, C; Takeuchi, S; et al. Immunohistochemical Localization of an Isoform of TRK-Fused Gene-Like Protein in the Rat Retina. ACTA HISTOCHEMICA ET CYTOCHEMICA 47:75-83(2014).
