TFDP2
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Official Full Name
transcription factor Dp-2 (E2F dimerization partner 2) -
Overview
The gene is a member of the transcription factor DP family. The encoded protein forms heterodimers with the E2F transcription factors resulting in transcriptional activation of cell cycle regulated genes. Alternative splicing results in multiple transcript variants. -
Synonyms
TFDP2;transcription factor Dp-2 (E2F dimerization partner 2);transcription factor Dp-2;Dp 2;DP2;FLJ39131;DKFZp313O196
Recombinant Proteins
- Human
- Chicken
- Rhesus macaque
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TFDP2-3199H | Recombinant Human TFDP2, GST-tagged | E.coli | Human | GST | N-term-350aa | |
| TFDP2-013H | Recombinant Human TFDP2 Protein, His-tagged | E.coli | Human | His | Full L. |
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| TFDP2-4096C | Recombinant Chicken TFDP2 | Mammalian Cells | Chicken | His |
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| TFDP2-4678R | Recombinant Rhesus monkey TFDP2 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| TFDP2-9803Z | Recombinant Zebrafish TFDP2 | Mammalian Cells | Zebrafish | His |
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| TFDP2-1131HCL | Recombinant Human TFDP2 293 Cell Lysate | HEK293 | Human | Non |
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| TFDP2-4494R | Recombinant Rhesus Macaque TFDP2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| TFDP2-4494R-B | Recombinant Rhesus Macaque TFDP2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
TFDP2 involved in several pathways and played different roles in them. We selected most pathways TFDP2 participated on our site, such as Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with TFDP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | SMAD3A,NIPBLB,BUB1,GADD45BB,HIST3H2BB,RAD21,SKA1,CEP78,E2F3,ORC1 |
Protein Function
TFDP2 has several biochemical functions, for example, DNA binding,RNA polymerase II transcription factor activity, sequence-specific DNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TFDP2 itself. We selected most functions TFDP2 had, and list some proteins which have the same functions with TFDP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | ETV3,CC2D1B,ZSCAN1,FOXO3,FOXO4,NPAS4A,FOXQ1B,FOXD4L1,SOX21,BMPR1A |
| transcription factor binding | TFDP1,ARRB1,PYDC3,MAPK1,LCOR,HTT,GATA6,GATA2,UBA2,PARD6A |
| transcription cofactor activity | HES6,TAF13,KAT2B,ZFP667,PHF21A,ZFP710,THRAP3,PTPN14,NSD1,AIRE |
| protein binding | LCORL,SLC22A5,CUL3,AKAP1,HMGB4,CDC14B,RUFY1,TAF1D,CHRNB2,CCL4 |
| transcription factor activity, sequence-specific DNA binding | PRDM2,ZNF501,RFX2,NFKB1,ZFP184,FOXN2B,PPARD,ZFP260,ZNF205,ZNF397 |
| protein domain specific binding | HOMER3,CALM,HIST1H4H,FOXA1,MRPS31,NR0B1,YWHAZ,PLAUR,IRS2,STRN4 |
| DNA binding | HOXB10A,FBXO21,ZBTB9,FOXG1,E2F7,TLX3B,MYCA,SIX3B,ZNF225,HIST1H3G |
Interacting Protein
TFDP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFDP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TFDP2.
E2F6;E2F4;RBL2;E7;RB1;YWHAE;LIN9;LIN54;LIN37
Resources
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References
- Chen, C; Lodish, HF; et al. Global analysis of induced transcription factors and cofactors identifies Tfdp2 as an essential coregulator during terminal erythropoiesis. EXPERIMENTAL HEMATOLOGY 42:464-476(2014).
- Wang, B; Hsu, SH; et al. Reciprocal Regulation of MicroRNA-122 and c-Myc in Hepatocellular Cancer: Role of E2F1 and Transcription Factor Dimerization Partner 2. HEPATOLOGY 59:555-566(2014).
