TES
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Official Full Name
testis derived transcript (3 LIM domains) -
Overview
Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene. -
Synonyms
TES;testis derived transcript (3 LIM domains);testin;DKFZP586B2022;TESS 2;TESS;TESS-2;MGC1146
Recombinant Proteins
- Zebrafish
- Human
- Rhesus macaque
- Rat
- Chicken
- Mouse
- Mammalian Cells
- E.coli
- HEK293
- His
- T7
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
TES involved in several pathways and played different roles in them. We selected most pathways TES participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TES were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TES has several biochemical functions, for example, mRNA 3-UTR binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TES itself. We selected most functions TES had, and list some proteins which have the same functions with TES. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | FAM133B,PCBP4,LARP7,NHP2,PSMC1,HNRNPD,CS,NXF3,RBM47,SFRS9 |
| mRNA 3-UTR binding | RNF20,CSDA,PUM1,SECISBP2,YBX2,TUT1,RBM24,CPEB4,ELAVL4,CPEB1A |
| protein binding | TPT1,PSPC1,MGAT5B,PTPN11,FAM96A,ANTXR1,KHDRBS3,APOBEC3G,TLDC2,PKD2L1 |
Interacting Protein
TES has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TES here. Most of them are supplied by our site. Hope this information will be useful for your research of TES.
ACTL7A;ENAH;Cep350;SOCS3;clpB;groL;q7ard3_yerpe;btuC3;cdiA;bglX2;rseA
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References
