TERF2IP
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Official Full Name
telomeric repeat binding factor 2, interacting protein -
Overview
Telomeric repeat-binding factor 2-interacting protein (TERF2IP, also known as RAP1) is a component of the Shelterin Complex, a multi-protein complex that binds and organizes telomeres into T-loop structures to prevent them from being recognized by the cel -
Synonyms
TERF2IP;telomeric repeat binding factor 2, interacting protein;telomeric repeat-binding factor 2-interacting protein 1;RAP1;hRap1;RAP1 homolog;TRF2-interacting telomeric protein 1;TERF2-interacting telomeric protein 1;repressor/activator protein 1
Recombinant Proteins
- Human
- Mouse
- Rat
- Chicken
- Zebrafish
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TERF2IP-3181H | Recombinant Human TERF2IP, His-tagged | E.coli | Human | His | 0-268aa | |
| TERF2IP-16645M | Recombinant Mouse TERF2IP Protein | Mammalian Cells | Mouse | His |
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| TERF2IP-30H | Recombinant Human TERF2IP protein, GST-tagged | Wheat Germ | Human | GST | 1 a.a. - 399 a.a. |
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| TERF2IP-6013R | Recombinant Rat TERF2IP Protein | Mammalian Cells | Rat | His |
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| TERF2IP-6038C | Recombinant Chicken TERF2IP | Mammalian Cells | Chicken | His |
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| TERF2IP-7954Z | Recombinant Zebrafish TERF2IP | Mammalian Cells | Zebrafish | His |
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| TERF2IP-1145HCL | Recombinant Human TERF2IP 293 Cell Lysate | HEK293 | Human | Non |
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| TERF2IP-5672R | Recombinant Rat TERF2IP Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| TERF2IP-5672R-B | Recombinant Rat TERF2IP Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| TERF2IP-681HF | Recombinant Full Length Human TERF2IP Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 399 amino acids |
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| TERF2IP-9131M | Recombinant Mouse TERF2IP Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TERF2IP-9131M-B | Recombinant Mouse TERF2IP Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TERF2IP involved in several pathways and played different roles in them. We selected most pathways TERF2IP participated on our site, such as Cell Cycle,Cellular Senescence,Cellular responses to stress, which may be useful for your reference. Also, other proteins which involved in the same pathway with TERF2IP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| DNA Damage/Telomere Stress Induced Senescence | HIST1H1C,TERF1,HIRA,POT1A,HTATIP,UBN1,HIST1H1B,ACD,EP400,HIST1H1D |
| Chromosome Maintenance | SMARCA5,TINF2,CENPK,RUVBL2,CENPW,WRAP53,DKC1,PANE1,CENPN,RBBP7 |
| Cellular responses to stress | NUP50,Txn1,KDM6B,ATG9B,HSPA13,RAD50,ATG4A,HIST1H1B,DPF1,TERF1 |
| Meiotic synapsis | SYCE1,TINF2,SUN1,POT1A,POT1,SYNE1,SYCP1,DIDO1,STAG2,TERF2 |
| Meiosis | MSH4,TEX12,ACD,SYNE1,TERF1,MND1,POT1,SUN1,SYCE1,TEX15 |
| Cellular Senescence | CDKN2D,HIST3H2BB,SUZ12A,CBX6A,E2F2,HIST4H4,TNIK,H1F0,TXN,AGO3 |
| Hypothetical Network for Drug Addiction | NISCH,ACTA1B,ACTA1,ZHX2,CX28.8,GJB7 |
| Cell cycle | HUS1,FKBP6,CCDC99,SMC1AL,USO1,LMNB1,UBE2V2,ORC6L,RAD50,SMARCA5 |
Protein Function
TERF2IP has several biochemical functions, for example, protein binding,NOT telomeric DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TERF2IP itself. We selected most functions TERF2IP had, and list some proteins which have the same functions with TERF2IP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MGST1,GREM1,MYL12A,NOTCH1,HIST1H2BB,MZF1,COPS7A,MKI67IP,GRIN2A,PIBF1 |
Interacting Protein
TERF2IP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TERF2IP here. Most of them are supplied by our site. Hope this information will be useful for your research of TERF2IP.
TERF2;XRCC6;ACD;SLX4
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