TECR
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Official Full Name
trans-2,3-enoyl-CoA reductase -
Overview
This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene. -
Synonyms
TECR;trans-2,3-enoyl-CoA reductase;glycoprotein, synaptic 2 , GPSN2, SC2;TER;glycoprotein, synaptic 2;synaptic glycoprotein SC2;SC2;GPSN2;MRT14
Recombinant Proteins
- Rhesus macaque
- Human
- Rat
- Bovine
- Mus musculus
- Mammalian Cell
- HEK293
- E.coli expression system
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
Involved Pathway
TECR involved in several pathways and played different roles in them. We selected most pathways TECR participated on our site, such as Fatty acid elongation,Biosynthesis of unsaturated fatty acids,Fatty acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with TECR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fatty acid elongation | PTPLAD2,ELOVL7A,ACOT5,ELOVL2,PTPLAD1,ELOVL3,HADH,HADHAA,ELOVL6,ACAA2 |
| Biosynthesis of unsaturated fatty acids | ACOX1,ELOVL5,FADS1,PTPLA,Scd1,ACAA1A,ACOX3,ACOT1,ACAA1,PECR |
| Fatty acid metabolism | ACSL3,ACSL3B,ACAA1A,Scd1,PTPLAD1,ACAA1,ACAT2,PECR,ELOVL2,PTPLA |
Protein Function
TECR has several biochemical functions, for example, oxidoreductase activity, acting on the CH-CH group of donors,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TECR itself. We selected most functions TECR had, and list some proteins which have the same functions with TECR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CHN2,STAC3,VPS18,THOC5,PITPNC1,GNMT,FKBP1A,PKP1,CRTAC1,LRDD |
| oxidoreductase activity, acting on the CH-CH group of donors | TECRB,PPP1R2,DPYDB,SRD5A2A,SRD5A3,SRD5A2B,GCDHA,GCDHB,ACOXL,TECRL |
Interacting Protein
TECR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TECR here. Most of them are supplied by our site. Hope this information will be useful for your research of TECR.
HACD2;ILK;CREB3;15-deoxy-delta(12,14;E2F3;XRCC3;ESR1;ARAF;MAPK4;MBOAT1;P;HIPK4;MAP1LC3A;DYRK4;DYRK1B
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References
- LESSIRE, R; BESSOULE, JJ; et al. OCCURRENCE AND CHARACTERIZATION OF A DEHYDRATASE ENZYME IN THE LEEK ICOSANOYL-COA SYNTHASE COMPLEX. BIOCHIMICA ET BIOPHYSICA ACTA 1169:243-249(1993).
