TEC
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Official Full Name
tec protein tyrosine kinase -
Overview
Tec kinase belongs to a structurally related subfamily of protein tyrosine kinases (PTKs) that includes Btk, Itk (also known as Emt or Tsk), Bmx, and Txk (or Rlk). With the exception of Txk, the members of this subfamily possess a long amino-terminal regi -
Synonyms
TEC;tec protein tyrosine kinase;tyrosine-protein kinase Tec;PSCTK4;MGC126760;MGC126762
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- Sf9 Cells
- Mammalian Cells
- Insect Cells
- E.coli
- HEK293
- GST
- His
- His&T7
- Non
- Avi&Fc&His
Involved Pathway
TEC involved in several pathways and played different roles in them. We selected most pathways TEC participated on our site, such as Osteoclast differentiation,T cell receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TEC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Osteoclast differentiation | FCGR3,MAP3K14,FCGR3A,LILRB4,AKT1,TNFRSF1A,NOX3,TRAF6,TAB2,PIK3R3 |
| T cell receptor signaling pathway | GSK3B,MAPK9,MAP2K7,RAF1,SLA1,MAPK13,PAK1,CD3E,NFATC2,PIK3CG |
Protein Function
TEC has several biochemical functions, for example, ATP binding,metal ion binding,non-membrane spanning protein tyrosine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TEC itself. We selected most functions TEC had, and list some proteins which have the same functions with TEC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | PRKCI,GSK3AA,MTHFD1,EP400,SRX1,ATP2B1B,TAF1,FDXACB1,MYH7B,OASL1 |
| metal ion binding | ZXDC,HCCS,AMHR2,PKM,DCST1,MOBKL2B,ZNF174,ZSCAN4F,ZC3H12A,TRIM7 |
| non-membrane spanning protein tyrosine kinase activity | FYN,PRKCD,BAZ1B,FES,MATK,TYK2,JAK3,JAK2A,JAK2B,YES1 |
| protein binding | CRADD,RBM8A,STX1A,UQCRC2,FOXP4,HTRA3,PFKFB2,KRTAP19-7,RBL1,MEMO1 |
| NOT receptor binding | STYK1,BTK,TXK,ITK,BMX,LGI1 |
| phospholipid binding | SYTL4,SHC1,SEC14L2,TICAM2,F10,PLEKHA3,PSD2,PICALMA,PSD4,RASAL1 |
Interacting Protein
TEC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TEC here. Most of them are supplied by our site. Hope this information will be useful for your research of TEC.
ERBB2;PTPRC;MET;KIT;PTPRB;PTPRG;FASLG;PTPN12;PTPRJ;GAB1;PTPRK;PTPRO;ASAP1;K15-M;WAS;MED28;pi3p;czc8004
Resources
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References
- Fernandez-Vega, I; Quiros, LM; et al. Bruton's tyrosine kinase (Btk) is a useful marker for Hodgkin and B cell non-Hodgkin lymphoma. VIRCHOWS ARCHIV 466:229-235(2015).
- Krueger, WS; Lucero, NE; et al. Evidence for Unapparent Brucella canis Infections among Adults with Occupational Exposure to Dogs. ZOONOSES AND PUBLIC HEALTH 61:509-518(2014).
