TFCP2
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Official Full Name
transcription factor CP2 -
Overview
Transcription factor LSF gene coding for the rate limiting enzyme in the production of dTTP. Disruption of LSF function results in apoptosis at S phase or to cell cycle arrest at the G1/S transition. -
Synonyms
TFCP2;transcription factor CP2;alpha-globin transcription factor CP2;CP2;LBP 1C;LSF;TFCP2C;SAA3 enhancer factor;SEF;LBP1C;LSF1D;Tcfcp2
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Chicken
- E.coli
- Sf9 Cells
- Mammalian Cells
- HEK293
- Insect Cells
- His
- GST
- Non
- Avi
- Fc
Involved Pathway
TFCP2 involved in several pathways and played different roles in them. We selected most pathways TFCP2 participated on our site, such as Signaling events mediated by HDAC Class I, which may be useful for your reference. Also, other proteins which involved in the same pathway with TFCP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling events mediated by HDAC Class I | NR2C1,SIRT7,PRMT5,FKBP3,GATA2,MXD1,WDR77,SIRT4,GATA1,SIRT5 |
Protein Function
TFCP2 has several biochemical functions, for example, DNA binding,protein C-terminus binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TFCP2 itself. We selected most functions TFCP2 had, and list some proteins which have the same functions with TFCP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | NR2E3,GCM2,HEY2,IRX5A,IRX1A,BCL2,HOXB3A,OTP,PPARA,RORAA |
| protein C-terminus binding | CACNA1B,CEP120,PABPC1,HAND2,HESX1,PXK,AGO2,YAP1,MAP2K1,ERCC3 |
| transcription factor activity, sequence-specific DNA binding | FOXA1,NR3C1,TLX2,ZIK1,ZNF165,ZFP30,TFDP2,CLOCKB,ZEB1,TFDP1B |
| protein binding | TMEM74,ALDOB,RIPK4,FASLG,MTAP,COMMD10,MIF,KRTAP4-11,PFDN2,SSTR3 |
| DNA binding | SSRP1A,ALX4B,RELA,ANKRD1,TXLNB,RDM1,RECQL,TNFAIP3,POLR1D,KDM2AA |
Interacting Protein
TFCP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFCP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TFCP2.
PHF1;E2F8;SHTN1;SDCBP;PITPNM1;FARS2;TSPAN12
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References
- Marini, MG; Porcu, L; et al. Regulation of the human HBA genes by KLF4 in erythroid cell lines. BRITISH JOURNAL OF HAEMATOLOGY 149:748-758(2010).
- Bing, ZY; Reddy, SAG; et al. Purification and characterization of the serum amyloid A3 enhancer factor. JOURNAL OF BIOLOGICAL CHEMISTRY 274:24649-24656(1999).
