TCERG1
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Official Full Name
transcription elongation regulator 1 -
Overview
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms. -
Synonyms
TCERG1;transcription elongation regulator 1;TAF2S, TATA box binding protein (TBP) associated factor, RNA polymerase II, S, 150kD;CA150;co activator of 150 kDa;TATA box binding protein (TBP) associated factor;RNA polymerase II;S;150kD;TATA box binding protein associated factor 2S;transcription factor CA150;Urn1;CA 150;Coactivator of 150 kDa;MGC133200;TAF2S;TATA box binding protein (TBP) associated factor RNA polymerase II S 150kD;TATA box binding protein associated factor RNA polymerase II S 150kD;co-activator of 150 kDa;TATA box-binding protein-associated factor 2S;TATA box binding protein (TBP)-associated factor, RNA polymerase II, S, 150kD
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TCERG1-3155H | Recombinant Human TCERG1, GST-tagged | E.coli | Human | GST | C-350aa | |
| TCERG1-1184HCL | Recombinant Human TCERG1 293 Cell Lysate | HEK293 | Human | Non |
|
Involved Pathway
TCERG1 involved in several pathways and played different roles in them. We selected most pathways TCERG1 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with TCERG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spliceosome | SNRNP70,U2AF1L4,SRSF7,SNRPD3,U2SURP,THOC2,BUD31,SNRNP40,U2AF1,CTNNBL1 |
Protein Function
TCERG1 has several biochemical functions, for example, RNA polymerase II repressing transcription factor binding,RNA polymerase II transcription corepressor activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TCERG1 itself. We selected most functions TCERG1 had, and list some proteins which have the same functions with TCERG1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PPP1R7,KIRREL2,DNAJC28,RPS11,QARS,PRKCZ,MLH1,SOX7,DNALI1,CD97 |
| RNA polymerase II transcription corepressor activity | TLE1,HEYL,NFIB,CTBP1,URI1,HDGF,HDAC1,RBBP8,TXLNB,N4BP2L2 |
| proline-rich region binding | WBP4,RABAC1,APBB1,YAP1,BAIAP2,BAIAP2L1,FAM59A,PRPF40A,PFN1,ABI2 |
| poly(A) RNA binding | SUPT6H,CRNKL1,RPN1,C22orf28,RPL19,H1FX,RPL10,COX4I2,ZNF326,ASS1 |
| RNA polymerase II repressing transcription factor binding | BBS4,GSC,BBS5,SP1,DMAP1,GATA6,GTF2A2,TBP,BBS7,MTA2 |
| transcription coactivator activity | TRIM32,POU2AF1,RBPMS,RNF20,ZSCAN1,LPIN2,SETD3,SUPT7L,NPAT,MKL1B |
Interacting Protein
TCERG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TCERG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TCERG1.
HTT;BARD1;Dlg4;WBP4;JUNB;SF3A2;WWOX;THRAP3;GRB2;CHD3;SETDB1
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