TBX6

  • Official Full Name

    T-box 6

  • Overview

    This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures. [provided by RefSeq, Aug 2008]

  • Synonyms

    TBX6;T-box 6;SCDO5;T-box transcription factor TBX6;T-box protein 6

Recombinant Proteins

  • Mouse
  • Chicken
  • Rat
  • Zebrafish
  • Human
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • Avi&Fc&His
Cat.# Product name Source (Host) Species Tag Protein Length Price
TBX6-16535M Recombinant Mouse TBX6 Protein Mammalian Cells Mouse His
TBX6-2238C Recombinant Chicken TBX6 Mammalian Cells Chicken His
TBX6-5977R Recombinant Rat TBX6 Protein Mammalian Cells Rat His
TBX6-8680Z Recombinant Zebrafish TBX6 Mammalian Cells Zebrafish His
TBX6-656HCL Recombinant Human TBX6 lysate HEK293 Human Non
TBX6-5636R Recombinant Rat TBX6 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
TBX6-5636R-B Recombinant Rat TBX6 Protein Pre-coupled Magnetic Beads HEK293 Rat
TBX6-9064M Recombinant Mouse TBX6 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
TBX6-9064M-B Recombinant Mouse TBX6 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    TBX6 involved in several pathways and played different roles in them. We selected most pathways TBX6 participated on our site, such as Neural Crest Differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBX6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neural Crest Differentiation ZIC1,LHX1,DMBX1,MBP,CTBP2,SOX5,FOXD3,MIA,LHX2,OLIG1

    Protein Function

    TBX6 has several biochemical functions, for example, DNA binding,RNA polymerase II activating transcription factor binding,RNA polymerase II transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBX6 itself. We selected most functions TBX6 had, and list some proteins which have the same functions with TBX6. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CSGALNACT2,BRD4,C1QL1,TMEM27,KIAA0947,DNAIC2,SOX4,TXLNG,SSRP1,RYBP
    RNA polymerase II transcription factor binding DHX9,GATA2A,GATA6,GATA3,NFATC1,TOX2,TAL1,MTA2,Ar,TBX20
    transcriptional repressor activity, RNA polymerase II transcription factor binding CREBBP,MINA,AHRRB,MLIP,RIMKLB,PITX2,T,BHLHE40,ELP2,EOMES
    transcription factor activity, sequence-specific DNA binding RAB11FIP4A,ARNT,RCAN1,SMAD2,HES1,SOX11,HIF1AB,ZNF187,POU5F3,ATF1
    RNA polymerase II activating transcription factor binding ISL1,DUSP26,SETD3,SMAD3,HNF4A,CREB1,ZFPM1,NFE2L2,BEX1,TBX3
    DNA binding HOXB5B,ZFP523,PBX1A,FOXL2,TRP53,RPAP1,HOXB3A,TAF9,KCNH7,PLSCR1

    Interacting Protein

    TBX6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBX6 here. Most of them are supplied by our site. Hope this information will be useful for your research of TBX6.

    TOX4;C1orf94;RBPMS;HSFY1;lepA;PRMT1

    Resources

    Research Area

    Early Mesodermal Lineage Markers
    Pluripotent Stem Cell Transcription Factors
    Ectodermal Lineage Markers
    Mesodermal Lineage Markers

    References

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