TBX19
-
Official Full Name
T-box 19 -
Overview
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog -
Synonyms
TBX19;T-box 19;T-box transcription factor TBX19;dj747L4.1;TBS 19;TPIT;T-box protein 19;T-box factor, pituitary;TBS19;FLJ26302;FLJ34085;FLJ34543
Recombinant Proteins
- Human
- Mouse
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Mammalian cells
- His
- Non
- His&Fc&Avi
- Myc&DDK
- Flag
Involved Pathway
TBX19 involved in several pathways and played different roles in them. We selected most pathways TBX19 participated on our site, such as Corticotropin-releasing hormone, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBX19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Corticotropin-releasing hormone | CYP11A1,KRT14,TFAP2A,ADRBK2,PARP1,CASP12,CRHR1,TRIM28,IVL,TCF4 |
Protein Function
TBX19 has several biochemical functions, for example, enhancer sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBX19 itself. We selected most functions TBX19 had, and list some proteins which have the same functions with TBX19. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| enhancer sequence-specific DNA binding | SOX9,LDB1,GATA3,HMGB2,KLF7B,GATA5,MYT1,TFAP2B,KLF6A,ISL1 |
| transcription factor activity, sequence-specific DNA binding | TFAP2B,KDM1A,IKZF3,NCOR1,HOXA2B,CBFB,TAL1,SKINT8,ZFP110,ZFP322A |
Interacting Protein
TBX19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBX19 here. Most of them are supplied by our site. Hope this information will be useful for your research of TBX19.
Resources
Related Services
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References
- Castellanos, R; Xie, Q; et al. Mammalian TBX1 Preferentially Binds and Regulates Downstream Targets Via a Tandem T-site Repeat. PLOS ONE 9:-(2014).
- Hersperger, AR; Martin, JN; et al. Increased HIV-specific CD8(+) T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression. BLOOD 117:3799-3808(2011).
