TBX10
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Official Full Name
T-box 10 -
Overview
This gene encodes a member of the T-box family of transcription factors. These transcription factors share a DNA-binding domain called the T-box, and play a role in several developmental processes including early embryonic cell fate and organogenesis. The encoded protein is a member of the T-box 1 subfamily. Mutations in this gene are thought to be a cause of isolated cleft lip with or without cleft palate. -
Synonyms
TBX10;T-box 10;T box 7 , TBX7;T-box transcription factor TBX10;TBX13;Dc;MGC129316;MGC129317;MmTBX7;T BOX 10;T box protein 10;T box protein 13;T-box protein 10;TBX10_HUMAN;Tbx7;T-box 7;T-box-containing transcriptional activator
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TBX10-16524M | Recombinant Mouse TBX10 Protein | Mammalian Cell | Mouse | His |
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| TBX10-1205HCL | Recombinant Human TBX10 293 Cell Lysate | HEK293 | Human | Non |
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| Tbx10-421M | Recombinant Mouse Tbx10 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| TBX10-4871H | Recombinant Human TBX10 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| TBX10-9057M | Recombinant Mouse TBX10 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TBX10-9057M-B | Recombinant Mouse TBX10 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TBX10 involved in several pathways and played different roles in them. We selected most pathways TBX10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TBX10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
TBX10 has several biochemical functions, for example, DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBX10 itself. We selected most functions TBX10 had, and list some proteins which have the same functions with TBX10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ZNF167,POLR1D,ZNF225,PAX6A,ZNF484,TAF4B,DMRT2,ZFP689,ELK4,ZNF711 |
| transcription factor activity, sequence-specific DNA binding | UBP1,REST,SIX4,ZFP184,ZNF323,ZFP27,E2F5,ZNF182,ATF4,SALL3B |
Interacting Protein
TBX10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBX10 here. Most of them are supplied by our site. Hope this information will be useful for your research of TBX10.
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References
- Boyoglu-Barnum, S; Chirkova, T; et al. Prophylaxis with a Respiratory Syncytial Virus (RSV) Anti-G Protein Monoclonal Antibody Shifts the Adaptive Immune Response to RSV rA2-line19F Infection from Th2 to Th1 in BALB/c Mice. JOURNAL OF VIROLOGY 88:10569-10583(2014).
- Curran, MA; Geiger, TL; et al. Systemic 4-1BB activation induces a novel T cell phenotype driven by high expression of Eomesodermin. JOURNAL OF EXPERIMENTAL MEDICINE 210:743-755(2013).
