TBL2
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Official Full Name
transducin (beta)-like 2 -
Overview
This gene encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23. -
Synonyms
TBL2;transducin (beta)-like 2;transducin beta-like protein 2;DKFZP43N024;WBSCR13;Williams Beuren syndrome chromosome region 13;WS betaTRP;DKFZp434N024;MGC134739;TBL 2;Transducin (beta) like 2;Transducin beta like 2;Transducin beta like 2 protein;WBSCR 13;Williams Beuren syndrome chromosomal region 13 protein;WS beta transducin repeats protein;WS beta-transducin repeats protein;Williams-Beuren syndrome chromosome region 13;WS-betaTRP
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TBL2-12036Z | Recombinant Zebrafish TBL2 | Mammalian Cells | Zebrafish | His |
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| TBL2-16515M | Recombinant Mouse TBL2 Protein | Mammalian Cells | Mouse | His |
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| TBL2-1212HCL | Recombinant Human TBL2 293 Cell Lysate | HEK293 | Human | Non |
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| TBL2-9049M | Recombinant Mouse TBL2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| TBL2-9049M-B | Recombinant Mouse TBL2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TBL2 involved in several pathways and played different roles in them. We selected most pathways TBL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TBL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TBL2 has several biochemical functions, for example, phosphoprotein binding,poly(A) RNA binding,protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBL2 itself. We selected most functions TBL2 had, and list some proteins which have the same functions with TBL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase binding | LIMS1,IFNAR2,SUFU,TRIM5,TP53,PAX6,DOK7,GPRC5B,TRP53,KIF20A |
| phosphoprotein binding | SFN,YWHAE,MS4A2,TOX3,APTX,THRAP3,PRKCSH,YWHAB,FKBP4,PAFAH1B1 |
| translation initiation factor binding | EIF2B4,ZFP259,EIF3BA,EIF3C,POLR2G,LARP1,LIN28A,TRIM32,CELF1,EIF3M |
| poly(A) RNA binding | ZNF385A,FIP1L1,MRPL32,FAM103A1,EFTUD2,LSM4,FBL,LUC7L2,SNRPD3,LARP2 |
Interacting Protein
TBL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TBL2.
PDPK1;USP44;ssdna_dtdg;MYC;ESR1;AGO1
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References
- Li, JW; Wang, J; et al. Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. EMBO JOURNAL 19:4342-4350(2000).
- Nawy, S; et al. The metabotropic receptor mGluR6 may signal through G(o), but not phosphodiesterase, in retinal bipolar cells. JOURNAL OF NEUROSCIENCE 19:2938-2944(1999).
