TBCE

  • Official Full Name

    tubulin folding cofactor E

  • Overview

    Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene.

  • Synonyms

    TBCE;tubulin folding cofactor E;KCS, Kenny Caffey syndrome , tubulin specific chaperone e;tubulin-specific chaperone E;HRD;KCS1;pac2;KCS;Tubulin specific chaperone e;Kenny-Caffey syndrome;tubulin-folding cofactor E

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • Rhesus macaque
  • Rat
  • E.coli
  • Mammalian Cell
  • HEK293
  • HEK293T
  • GST
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi

    Involved Pathway

    TBCE involved in several pathways and played different roles in them. We selected most pathways TBCE participated on our site, such as Metabolism of proteins,Post-chaperonin tubulin folding pathway,Protein folding, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBCE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Post-chaperonin tubulin folding pathway TBCB,ARL2,TBCA,TBCC,SERPINA7,TBCD
    Protein folding FBXL5,TBCB,TBCA,CCT6A,PFDN5,FBXW5,PFDN4,PFDN6,FBXW4,TBCC
    Metabolism of proteins KLHDC3,CTAGE5,TIMM44,TIMM8A,DDIT3,TOMM6,IGFBP2,MGAT4B,MAN1B1,B3GNT6

    Protein Function

    TBCE has several biochemical functions, for example, chaperone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBCE itself. We selected most functions TBCE had, and list some proteins which have the same functions with TBCE. You can find most of the proteins on our site.

    Function Related Protein
    chaperone binding DNAJA3B,TP53,AHSA1,TG,BAG4,ATP1A3,CDC37,DNAJC3,TRP53,TBCD

    Interacting Protein

    TBCE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBCE here. Most of them are supplied by our site. Hope this information will be useful for your research of TBCE.

    HLA-B

    Resources

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