TBCD
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Official Full Name
tubulin folding cofactor D -
Overview
Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. -
Synonyms
TBCD;tubulin folding cofactor D;tubulin specific chaperone d;tubulin-specific chaperone D;Beta tubulin cofactor D;Beta-tubulin cofactor D;KIAA0988;SSD 1;SSD-1;SSD1;TBCD_HUMAN;tfcD;Tubulin-folding cofactor D
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TBCD-3134H | Recombinant Human TBCD, His-tagged | E.coli | Human | His | 0-270AA | |
| TBCD-2029C | Recombinant Chicken TBCD | Mammalian Cells | Chicken | His |
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| TBCD-1744HCL | Recombinant Human TBCD cell lysate | Human | Non |
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Involved Pathway
TBCD involved in several pathways and played different roles in them. We selected most pathways TBCD participated on our site, such as Metabolism of proteins,Post-chaperonin tubulin folding pathway,Protein folding, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBCD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Post-chaperonin tubulin folding pathway | SERPINA7,TBCE,TBCB,TBCA,ARL2,TBCC |
| Metabolism of proteins | PIGK,CST3,TRAPPC9,KIFC3,KDELR3,SENP1,ST8SIA2,PFDN5,GATA6,F9A |
| Protein folding | FBXW9,CCT7,PFDN2,TBCC,NOP56,TBCA,TBCB,FBXL5,FBXW4,KIFC3 |
Protein Function
TBCD has several biochemical functions, for example, GTPase activator activity,beta-tubulin binding,chaperone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBCD itself. We selected most functions TBCD had, and list some proteins which have the same functions with TBCD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | FRA10AC1,PNMA2,PNOC,TFAP4,CASK,SMCO3,KCNJ3,ZKSCAN3,FSTL5,SULT4A1 |
| GTPase activator activity | RGS5B,TBC1D14,TBC1D8,ARRB1,AGFG1B,LLGL2,ARHGDIB,RANGAP1,ARHGAP40,TBC1D3 |
| chaperone binding | FGB,SERPINA7,CDC37L1,TG,C1orf182,SLC25A17,HSCB,TSACC,PARK2,TRP53 |
| beta-tubulin binding | ARL8A,CCT5,AKAP1,GABARAPL2,SLC6A2,EMD,BBS4,SIRT2,GABARAPL1,RGS2 |
Interacting Protein
TBCD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBCD here. Most of them are supplied by our site. Hope this information will be useful for your research of TBCD.
ACD;ARL2;ARL3;Tubb4b;Tubb5;IKBKG;SMAD9;DEXI;XRCC6;POLR2I;TERF1;POT1;1C
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