TAX1BP1
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Official Full Name
Tax1 (human T-cell leukemia virus type I) binding protein 1 -
Overview
Tax1-binding protein (TAX1BP) 1 is an essential regulator of innate immunity and was originally identified in a yeast two-hybrid screen as a human T-lymphotropic virus Type 1 (HTLV-1) Tax1-binding protein and named TXBP151 (1-3). Independently, TAX1BP1 wa -
Synonyms
TAX1BP1;Tax1 (human T-cell leukemia virus type I) binding protein 1;tax1-binding protein 1;CALCOCO3;TXBP151;TRAF6-binding protein;T6BP
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Chicken
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Avi
- Fc
Involved Pathway
TAX1BP1 involved in several pathways and played different roles in them. We selected most pathways TAX1BP1 participated on our site, such as Death Receptor Signalling,Immune System,Innate Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAX1BP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of TNFR1 signaling | SHARPIN,USP2,OTUD7B,USP4,RNF31,CLIP3,SHRPRBCK1R,RBCK1,OTULIN,FAM105B |
| Signal Transduction | AMOTL2A,PTGDR2,FABP11B,RGS14,DLK1,PPY,DNAL4B,HECW1B,OBSCN,OXER1 |
| TNF signaling | OTULIN,SHRPRBCK1R,RBCK1,OTUD7B,SHARPIN,TAX1BP1B,OTULINB,USP4,FAM105B,USP2 |
| Innate Immune System | LRRFIP1,POLR3C,ALCAMB,TXNIPB,CYLD,PCBP2,GZMM,TXNIPA,CD180,NLRC5 |
| Negative regulators of RIG-I/MDA5 signaling | CYLD,PCBP2,HERC5,RNF135,NLRC5,TAX1BP1B,RNF216 |
| Death Receptor Signalling | GNB2L1,TAB1,FAM105B,USP2,SHRPRBCK1R,OTULINB,RBCK1,TAX1BP1B,SHARPIN,CLIP3 |
| Immune System | DYNLL2,CD200R1,SIGLEC10,DCTN6,CTSD,SPSB4,RAP1GAP2,EIF4E3,HBL3,KPNA5 |
| RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways | RNF135,NLRC5,TAX1BP1B,RNF216,TANK,PCBP2,HERC5 |
Protein Function
TAX1BP1 has several biochemical functions, for example, kinase binding,metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAX1BP1 itself. We selected most functions TAX1BP1 had, and list some proteins which have the same functions with TAX1BP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | GNAT1,ROR2,ZBTB37,PRG4B,ZFP259,ZNF792,IKZF5,AOX4,VDRB,WBP7 |
| protein binding | KIF2A,BTG3,BBS4,SNX12,EIF3D,REEP1,RBBP8,PSMC4,OLFM3,KLF4 |
| kinase binding | PTPN22,RB1,GFAP,STUB1,PPP1R9B,PPP2R5A,JAKMIP1,ATF5,PRPSAP1,BTG1 |
Interacting Protein
TAX1BP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAX1BP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAX1BP1.
TRAF6;RALBP1;RNF11;TSHZ3;a8kad6_human;LGALS8
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