TAS2R50
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Official Full Name
taste receptor, type 2, member 50 -
Overview
TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and;mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 (PubMed;12584440)). See also TAS2R10 (MIM 604791). -
Synonyms
TAS2R50;taste receptor, type 2, member 50;taste receptor type 2 member 50;T2R51;T2R50;taste receptor type 2 member 51;TAS2R51
Recombinant Proteins
- Macaca mulatta
- Pan paniscus
- Papio hamadryas (Hamadryas baboon)
- Pan troglodytes
- Human
- Gorilla gorilla gorilla (Western lowland gorilla)
- Pongo Pygmaeus
- E.coli
- His
Involved Pathway
TAS2R50 involved in several pathways and played different roles in them. We selected most pathways TAS2R50 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TAS2R50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
TAS2R50 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TAS2R50 itself. We selected most functions TAS2R50 had, and list some proteins which have the same functions with TAS2R50. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
TAS2R50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAS2R50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAS2R50.
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References
- Deane, AM; Rayner, CK; et al. The Effects of Critical Illness on Intestinal Glucose Sensing, Transporters, and Absorption. CRITICAL CARE MEDICINE 42:57-65(2014).
- Gees, M; Alpizar, YA; et al. Differential Effects of Bitter Compounds on the Taste Transduction Channels TRPM5 and IP3 Receptor Type 3. CHEMICAL SENSES 39:295-311(2014).
- Akao, H; Polisecki, E; et al. KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly. ATHEROSCLEROSIS 220:456-462(2012).
