TAS2R4
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Official Full Name
taste receptor, type 2, member 4 -
Overview
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor;superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These;apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This;gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that;influence bitter perception. -
Synonyms
TAS2R4;taste receptor, type 2, member 4;taste receptor type 2 member 4;T2R4;Candidate taste receptor T2R4;MGC163311;Taste receptor T2R4
Recombinant Proteins
- Pan troglodytes
- Papio hamadryas (Hamadryas baboon)
- Human
- Rat
- Mus musculus
- Pan paniscus
- Pongo Pygmaeus
- Gorilla gorilla gorilla (Western lowland gorilla)
- E.coli
- His
Involved Pathway
TAS2R4 involved in several pathways and played different roles in them. We selected most pathways TAS2R4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TAS2R4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
TAS2R4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TAS2R4 itself. We selected most functions TAS2R4 had, and list some proteins which have the same functions with TAS2R4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
TAS2R4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAS2R4 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAS2R4.
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References
- Yasumatsu, K; Manabe, T; et al. Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice. JOURNAL OF PHYSIOLOGY-LONDON 593:1021-1034(2015).
