TAS2R3
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Official Full Name
taste receptor, type 2, member 3
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Overview
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless taste receptor genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. -
Synonyms
TAS2R3; taste receptor, type 2, member 3; taste receptor type 2 member 3; T2R3; candidate taste receptor T2R3;
- Cell & Tissue Lysates
- Recombinant Proteins
- Gorilla gorilla gorilla (Western lowland gorilla)
- Homo sapiens (Human)
- Human
- Mus musculus (Mouse)
- Pan paniscus (Pygmy chimpanzee) (Bonobo)
- Pan troglodytes (Chimpanzee)
- Papio hamadryas (Hamadryas baboon)
- Pongo pygmaeus (Bornean orangutan)
- Rattus norvegicus (Rat)
- Zebrafish
- E.coli expression system
- HEK293
- Mammalian Cell
- His
- Non
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | TAS2R3-1244HCL | Recombinant Human TAS2R3 293 Cell Lysate | HEK293 | Non |
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| Gorilla gorilla gorilla (Western lowland gorilla) | RFL19250GF | Recombinant Full Length Gorilla Gorilla Gorilla Taste Receptor Type 2 Member 3(Tas2R3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-315) |
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| Homo sapiens (Human) | RFL28009HF | Recombinant Full Length Human Taste Receptor Type 2 Member 3(Tas2R3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-316) |
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| Mus musculus (Mouse) | RFL18967MF | Recombinant Full Length Mouse Taste Receptor Type 2 Member 3(Tas2R3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-316) |
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| Pan paniscus (Pygmy chimpanzee) (Bonobo) | RFL10484PF | Recombinant Full Length Pan Paniscus Taste Receptor Type 2 Member 3(Tas2R3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-315) |
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| Pan troglodytes (Chimpanzee) | RFL2815PF | Recombinant Full Length Pan Troglodytes Taste Receptor Type 2 Member 3(Tas2R3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-315) |
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| Papio hamadryas (Hamadryas baboon) | RFL13995PF | Recombinant Full Length Papio Hamadryas Taste Receptor Type 2 Member 3(Tas2R3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-315) |
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| Pongo pygmaeus (Bornean orangutan) | RFL3909PF | Recombinant Full Length Pongo Pygmaeus Taste Receptor Type 2 Member 3(Tas2R3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-315) |
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| Rattus norvegicus (Rat) | RFL4111RF | Recombinant Full Length Rat Taste Receptor Type 2 Member 3(Tas2R3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-316) |
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| Zebrafish | TAS2R3-6000Z | Recombinant Zebrafish TAS2R3 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
TAS2R3 involved in several pathways and played different roles in them. We selected most pathways TAS2R3 participated on our site, such as Class C/3 (Metabotropic glutamate/pheromone receptors), G alpha (i) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAS2R3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | TAS2R13;TAS2R16;GPRC6A;TAS2R3;TAS2R7;CASR |
| G alpha (i) signalling events | CCR1;CHRM2;SOUL4;APLN;CCL19A.2;RGS6;SSTR2;APLNR;CXCL11.8 |
| GPCR downstream signaling | CCR9;TAS2R3;PTH2;AKAP13;KALRNB;UTS2;PTHLH;PTHRP2;NMS |
| GPCR ligand binding | EDN3;S1PR3;PROK1;EDNRAB;NMS;HEBP1;RHOL;TAC2;OPN1MW |
| Signal Transduction | FAM13A;CGNB;ARHGAP20;THBS3B;CDC73;USP9;CD97;EVC;RAMP2 |
| Signaling by GPCR | OPN1SW1;PRLH;SOUL4;ARHGEF18;HEBP1;GPR77;NMBA;NMB;GNA13B |
| Taste transduction | TAS2R107;TAS2R106;TAS2R38;TAS2R7;TRPM5;GNB3;TAS2R109;TAS2R129;GNG13 |
TAS2R3 has several biochemical functions, for example, bitter taste receptor activity, taste receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAS2R3 itself. We selected most functions TAS2R3 had, and list some proteins which have the same functions with TAS2R3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| bitter taste receptor activity | TAS2R118;TAS2R16;TAS2R121;TAS2R140;TAS2R13;TAS2R3;TAS2R138;TAS2R108;TAS2R137 |
| taste receptor activity | TAS2R139;TAS2R138;TAS2R140;TAS1R1;TAS1R2;TAS2R108;TAS2R144;GPR120;TAS2R143 |
TAS2R3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAS2R3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAS2R3.
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