TAS2R3
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Official Full Name
taste receptor, type 2, member 3 -
Overview
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless taste receptor genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. -
Synonyms
TAS2R3;taste receptor, type 2, member 3;taste receptor type 2 member 3;T2R3;candidate taste receptor T2R3
Recombinant Proteins
- Zebrafish
- Human
- Pan paniscus
- Papio hamadryas (Hamadryas baboon)
- Mus musculus
- Gorilla gorilla gorilla (Western lowland gorilla)
- Pan troglodytes
- Pongo Pygmaeus
- Rat
- Mammalian Cells
- HEK293
- E.coli
- His
- Non
Involved Pathway
TAS2R3 involved in several pathways and played different roles in them. We selected most pathways TAS2R3 participated on our site, such as Class C/3 (Metabotropic glutamate/pheromone receptors),G alpha (i) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAS2R3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | GPRC6A,TAS2R13,TAS2R16,TAS2R7,CASR |
| Signaling by GPCR | NMBB,CCL35.1,CCRL2,PENKA,HEBP1,NET1,RGS4,ANXA1C,RAMP3,OPN5 |
| Taste transduction | TAS2R144,TAS2R134,TAS2R113,GNAT3,TAS2R38,ITPR3,TAS2R40,TRPM5,TAS2R106,TAS2R110 |
| GPCR ligand binding | PROKR2,APLNR,HCRT,INSL5,TAC2,OPN1LW2,ADORA1,ZFPM2B,AMCF-II,AGT |
| GPCR downstream signaling | DGKG,KISS1,PPY,PTHLH,CRHR1,OR56A1,CRHB,CHRM3,RLN3A,VIP |
| G alpha (i) signalling events | RHOL,CCR1,SOUL3,SSTR5,GPR55,OPN1SW,CXCL11.8,HEBP1,OXER1,APLN |
| Signal Transduction | OXER1,DEPDC7,EMR1,GUCA1E,CBY1,OR10A5,ROR1,GRK7,ABI1B,RYK |
Protein Function
TAS2R3 has several biochemical functions, for example, bitter taste receptor activity,taste receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAS2R3 itself. We selected most functions TAS2R3 had, and list some proteins which have the same functions with TAS2R3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| taste receptor activity | TAS2R137,TAS2R7,TAS2R143,TAS2R138,TAS2R136,TAS2R144,TAS1R3,TAS2R139,TAS1R2,TAS2R108 |
| bitter taste receptor activity | TAS2R137,TAS2R13,TAS2R114,TAS2R136,TAS2R38,TAS2R144,TAS2R121,TAS2R138,TAS2R118,TAS2R108 |
Interacting Protein
TAS2R3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAS2R3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAS2R3.
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