TAS2R16
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Official Full Name
taste receptor, type 2, member 16 -
Overview
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. -
Synonyms
TAS2R16;taste receptor, type 2, member 16;taste receptor type 2 member 16;T2R16;candidate taste receptor T2R16
Recombinant Proteins
- Rhesus macaque
- Human
- Gorilla gorilla gorilla (Western lowland gorilla)
- Pongo Pygmaeus
- Pan paniscus
- Papio hamadryas (Hamadryas baboon)
- Mus musculus
- Rat
- Pan troglodytes
- Mammalian Cells
- HEK293
- E.coli
- His
- Non
- Avi
- Fc
Involved Pathway
TAS2R16 involved in several pathways and played different roles in them. We selected most pathways TAS2R16 participated on our site, such as Class C/3 (Metabotropic glutamate/pheromone receptors),G alpha (i) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAS2R16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| GPCR ligand binding | CASR,GHRH,OPN1SW,APLNR,TAC3,PTH,EDN2,SCT,PROKR2,PTHLHA |
| Taste transduction | KCNB1,PRKACG,GNB3,TAS1R1,TAS2R138,TAS2R125,TAS2R40,TAS2R134,TAS1R2,TAS2R130 |
| Signal Transduction | OR52B4,WIPF2,ARHGAP33,ARHGAP1,IFT172,SCUBE2,DNER,GPR39,CDC42EP5,RAB6A |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | TAS2R3,GPRC6A,TAS2R13,TAS2R7,CASR |
| Signaling by GPCR | VIP,OPN4B,GPR55A,VIP2,OPN1SW1,NMB,RGS11,HCAR1-2,FGD2,CXCR7B |
| GPCR downstream signaling | EDN3,PTHLH,PENKB,CCL19A.2,OXGR1A.3,GHRH,TRPC6A,CRHR2,NMB,GNA13 |
| G alpha (i) signalling events | OXGR1A.1,SSTR1,PNOC,ANXA1,OPN1MW,LPAR1,GPR55A,CCR1,RGS11,GAL |
Protein Function
TAS2R16 has several biochemical functions, for example, bitter taste receptor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAS2R16 itself. We selected most functions TAS2R16 had, and list some proteins which have the same functions with TAS2R16. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| bitter taste receptor activity | TAS2R137,TAS2R7,TAS2R138,TAS2R114,TAS2R40,TAS2R3,TAS2R13,TAS2R136,TAS2R121,TAS2R130 |
| protein binding | GSTM5,CAV2,MEA1,PDE6H,MEI4,MPZL1L,FKBP5,FHIT,CCND1,LAX1 |
Interacting Protein
TAS2R16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAS2R16 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAS2R16.
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