TALDO1
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Official Full Name
transaldolase 1 -
Overview
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. -
Synonyms
TALDO1;transaldolase 1;transaldolase;Dihydroxyacetone transferase;EC 2.2.1.2;EPS8L2;Glycerone transferase;TAL;TAL H;TALDO;TALDOR;TALH;TAL-H
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Chicken
- Rat
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- Mammalian cells
- His
- His&T7
- Non
- Myc&DDK
- GST
- His&Fc&Avi
Involved Pathway
TALDO1 involved in several pathways and played different roles in them. We selected most pathways TALDO1 participated on our site, such as Pentose phosphate pathway,Metabolic pathways,Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with TALDO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | SQLEA,DGAT1A,ENPP3,ALDH3A2A,PTDSS1A,WBSCR17,TDO2B,MAN1B1,NTPCR,HPDA |
| Carbon metabolism | PCCB,FH,PFKMB,FBP1A,HAO2,ENO1,PKLR,ALDOA,SDHA,DLST |
| Biosynthesis of amino acids | PGK1,PKM2,THA1,PGK2,GOT1,GAPDH,ASS1,PYCRL,GLULB,GPT2 |
| Pentose phosphate pathway | ALDOCB,ALDOB,TKTL1,FBP2,PGD,TKTL2,GPIB,G6PDX,PGM1,RPE |
Protein Function
TALDO1 has several biochemical functions, for example, monosaccharide binding,protein binding,sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TALDO1 itself. We selected most functions TALDO1 had, and list some proteins which have the same functions with TALDO1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | AIPL1,LPXN,BSG,AKR1C1,TSC1,PRDX1,PHOSPHO2,IQCB1,TNNT1,ARL3 |
| monosaccharide binding | FBP1,UPK1A,Siglece,PGLS,GPR19,RPIA,GPI,GPI1 |
Interacting Protein
TALDO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TALDO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TALDO1.
TERF2IP;EIF1B;MCC;EIF6;ARF6;IKBKE;TRAF6;LSM8;TERF1;CHD3;TERF2;ZHX1;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;VCAM1
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