TAF9
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Official Full Name
Taf9p -
Overview
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly -
Synonyms
TAF9;Taf9p;AK6;CGI 137;CINAP;CIP;HGNC:11542;MGC:1603;MGC:3647;MGC:5067;TAF17;TAF2G;TAF9 RNA polymerase II TATA box binding protein (TBP)-associated factor;TAFII31;TAFII32;TAFIID32;TBP associated factor 17 kDa;TBP associated factor 9;Transcription initiation factor TFIID subunit 9;YMR236W;Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H3
Recombinant Proteins
- Human
- Cynomolgus
- Mouse
- Zebrafish
- Rhesus macaque
- Chicken
- Rat
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Avi
- Fc
Involved Pathway
TAF9 involved in several pathways and played different roles in them. We selected most pathways TAF9 participated on our site, such as Basal transcription factors, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Basal transcription factors | GTF2A1,TAF10,GTF2F2B,TAF11,TAF5,GTF2H5,GTF2F2,TBPL1,TAF6L,GTF2H2 |
Protein Function
TAF9 has several biochemical functions, for example, ATPase binding,C2H2 zinc finger domain binding,DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF9 itself. We selected most functions TAF9 had, and list some proteins which have the same functions with TAF9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| C2H2 zinc finger domain binding | GATA2,EHMT1,LEF1,WT1,THAP7,HMGA2,ZXDC,EHMT2,U2AF2,EBF1 |
| transcription coactivator activity | SUB1A,MED13,MKL1,MYSM1,SAP130,MNT,ING4,DDX17,JUN,MED14 |
| contributes_to histone acetyltransferase activity | KAT2A,TADA3,SAP130,KAT5,TAF10,SUPT7L,TAF12,TAF6L,ING3,ELP4 |
| p53 binding | AXIN1,TRIM24,SMARCB1,BANP,BCL2L12,ZNF385D,TP53RK,EHMT2,SIRT1,AAAS |
| activating transcription factor binding | EEF1D,HDAC1,SMAD2,GATA4,PRDM16,MEF2D,EP300,RELA,HDAC7,ATOH8 |
| transcription regulatory region DNA binding | AIRE,PPARG,ARID5A,SOX2,SOX6,YAP1,CTCF,NKX3,NKX2-1,CDK9 |
| protein heterodimerization activity | NFYBA,ADD1,BNIP3L,CYBB,ABTB2,EXT2,BTBD11,LIMK1,TYRP1,SYT10 |
| protein binding | FBXO34,MCCC1,WNT2,C9orf16,FGFR1OP2,EPB41L1,USP54,PSEN1,CCDC11,FGF13 |
| ATPase binding | PGR,SYVN1,GRIN2A,EZR,DNAJB1,ATP6V0A1,ATP6V0A2,PTPN3,USP25,DERL1 |
Interacting Protein
TAF9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF9 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF9.
DRAP1;TAF6L;KPNA1;RPS14;KAT2B
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References
- Xie, GQ; Yu, ZS; et al. E(y)1/TAF9 mediates the transcriptional output of Notch signaling in Drosophila. JOURNAL OF CELL SCIENCE 127:3830-3839(2014).
- Ramachandran, PS; Boudreau, RL; et al. Nonallele Specific Silencing of Ataxin-7 Improves Disease Phenotypes in a Mouse Model of SCA7. MOLECULAR THERAPY 22:1635-1642(2014).
