TAF7L
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Official Full Name
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa -
Overview
This gene is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
TAF7L;TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa;TAF2Q, TATA box binding protein (TBP) associated factor, RNA polymerase II, Q;transcription initiation factor TFIID subunit 7-like;cancer/testis antigen 40;CT40;FLJ23157;TAF2Q;TAF7 like RNA polymerase II, TATA box binding protein (TBP) associated factor;TATA box binding protein-associated factor, RNA polymerase II, Q;TBP associated factor, RNA polymerase II, Q;TBP-associated factor, RNA polymerase II, Q;RNA polymerase II TBP-associated factor subunit Q;TATA box-binding protein-associated factor 50 kDa;transcription initiation factor TFIID 50 kDa subunit
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TAF7L-16402M | Recombinant Mouse TAF7L Protein | Mammalian Cell | Mouse | His |
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| TAF7L-1226H | Recombinant Human TAF7L protein, His&Myc-tagged | E.coli | Human | His&Myc | 1-302aa |
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| TAF7L-8972M | Recombinant Mouse TAF7L Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TAF7L-8972M-B | Recombinant Mouse TAF7L Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TAF7L involved in several pathways and played different roles in them. We selected most pathways TAF7L participated on our site, such as Basal transcription factors, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF7L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Basal transcription factors | TAF4B,TAF6L,TAF1,GTF2F1,GTF2H3,TAF10,GTF2A2,CDK7,TAF1L,TAF9B |
Protein Function
TAF7L has several biochemical functions, for example, histone acetyltransferase binding,protein binding,transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF7L itself. We selected most functions TAF7L had, and list some proteins which have the same functions with TAF7L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription coactivator activity | ARL2BP,MED21,ELF3,JUNB,CDK7,SUPT3H,SRA1,CALCOCO1,MED31,SMARCB1 |
| transcription factor binding | POU5F1,SMAD3,TP73,AGTR2,BPTF,PIAS2,DRAP1,HDAC3,HDAC8,SUMO1 |
| transcription regulatory region DNA binding | TP73,TFE3,ZNF174,ZNF567,MTERFD1,IKZF4,ZFHX3,BRD7,KLF15,CTCF |
| protein binding | NCAPD2,PTGES3,C2orf51,BEND7,RCAN1,CDC42,FAM9C,IDE,AKAP6,DLG4 |
| histone acetyltransferase binding | KAT2B,FOXP3,ETS1,NR4A3,PAX6,CREB1,TP53,HIF1A,SIRT2,SP1 |
Interacting Protein
TAF7L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF7L here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF7L.
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References
- Zhou, HY; Wan, B; et al. TAF7L Modulates Brown Adipose Tissue Formation. ELIFE 3:-(2014).
- Zhou, HY; Grubisic, I; et al. Taf7l cooperates with Trf2 to regulate spermiogenesis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:16886-16891(2013).
