TAF3
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Official Full Name
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -
Overview
The highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box-binding;protein (TBP; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter;recognition and selectivity and act as antiapoptotic factors (Gangloff et al., 2001 (PubMed 11438666)). -
Synonyms
TAF3;TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa;TAF3 RNA polymerase II, TATA box binding protein (TBP) associated factor, 140 kD;transcription initiation factor TFIID subunit 3;TAF140;TAFII140;140 kDa TATA box-binding protein-associated factor;Bip2 protein;TAF(II)14;TAF3 RNA polymerase II TATA box binding protein (TBP)-associated factor;TAFII155 protein;TBP-associated factor 3;Transcription initiation factor TFIID 140 kDa subunit;TAF(II)140;OTTHUMP00000019072;RNA polymerase II transcription factor TAFII140;TAFII-140
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TAF3-3104H | Recombinant Human TAF3, GST-tagged | E.coli | Human | GST | 443-721aa | |
| TAF3-2537C | Recombinant Chicken TAF3 | Mammalian Cell | Chicken | His |
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| TAF3-3834Z | Recombinant Zebrafish TAF3 | Mammalian Cell | Zebrafish | His |
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Involved Pathway
TAF3 involved in several pathways and played different roles in them. We selected most pathways TAF3 participated on our site, such as Basal transcription factors,Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Herpes simplex infection | IL6,THOC4,IKBKG,CSNK2A2A,SRSF5B,IFNA17,SRSF6,TNFRSF1A,IFNA13,HLA-F |
| Basal transcription factors | TAF1L,TAF4B,GTF2A1L,GTF2A1,GTF2IRD1,GTF2H2C_2,TAF15,GTF2A2,TAF6L,GTF2H1 |
Protein Function
TAF3 has several biochemical functions, for example, p53 binding,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF3 itself. We selected most functions TAF3 had, and list some proteins which have the same functions with TAF3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SNX18,ADARB1,CNOT7,RUSC2,PPP2R5E,FBXO2,TRIM69,PAK1,TFAP2C,PTK6 |
| zinc ion binding | CECR1,GTF2B,ZCCHC12,RC3H2,LIMD2,CNOT4B,ITGB1BP2,BRCA1,ZNF257,RYBP |
| p53 binding | RCHY1,MAPKAPK5,NUAK1,NTRK3,EP300,RNF20,ZFP385C,USP10,GATA1,CDK5 |
Interacting Protein
TAF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF3.
H3F3A;TAF5;SMAD2;h3_peptide_2-18;MED26;MZT1
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References
- Alpern, D; Langer, D; et al. TFIID subunit TAF4 directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation. ELIFE 3:-(2014).
- van Nuland, R; Schram, AW; et al. Multivalent Engagement of TFIID to Nucleosomes. PLOS ONE 8:-(2013).
