TAF1A
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Official Full Name
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa -
Overview
This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms. -
Synonyms
TAF1A;TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa;TATA box binding protein (TBP) associated factor, RNA polymerase I, A, 48kD;TATA box-binding protein-associated factor RNA polymerase I subunit A;SL1;TAFI48;RAFI48;TATA box binding protein associated factor 1A;TATA box binding protein associated factor RNA polymerase I subunit A;TBP associated factor RNA polymerase I 48 kDa;Transcription factor SL1;SL1, 48kD subunit;OTTHUMP00000035653;OTTHUMP00000035654;OTTHUMP00000035655;TBP-associated factor 1A;TATA box-binding protein-associated factor 1A;transcription;MGC:17061
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- Rat
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
TAF1A involved in several pathways and played different roles in them. We selected most pathways TAF1A participated on our site, such as Epigenetic regulation of gene expression,Gene Expression,Negative epigenetic regulation of rRNA expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA Polymerase I Chain Elongation | TAF1C,TAF1D,UBTF,CD3EAP,CBX3,CBX3A,TAF1B,EFCAB11 |
| RNA Polymerase I Promoter Escape | TAF1C,TAF1D,TAF1B,RRN3,UBTF,EFCAB11,CD3EAP |
| NoRC negatively regulates rRNA expression | SIN3B,BAZ2A,SAP30L,DNMT1,DNMT3B,EFCAB11,TAF1B,TAF1C,CD3EAP,SUDS3 |
| Epigenetic regulation of gene expression | JARID2,DNMT1,EFCAB11,DNMT3B,RRP8,RBB4L,UHRF1,EED,SMARCA5,DNMT3L |
| Gene Expression | RPP14,PUS7,SFRS3A,ZNF71,MTERF,ZNF584,SUPT4H1,ZNF157,MTA2,ZNF266 |
| RNA Polymerase I Promoter Clearance | CD3EAP,MTA1,RRN3,MTA2,EFCAB11,EHMT2,MBD3,TAF1D,GATAD2A,CHD4A |
| Negative epigenetic regulation of rRNA expression | SAP30,SAP30BP,DNMT3B,RRP8,CD3EAP,SAP18,DNMT1,SUDS3,BAZ2A,EFCAB11 |
| RNA Polymerase I Transcription | GATAD2A,PTRFB,MTA3,EFCAB11,GATAD2B,CHD4,RRN3,TAF1D,CBX3,TAF1B |
Protein Function
TAF1A has several biochemical functions, for example, DNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF1A itself. We selected most functions TAF1A had, and list some proteins which have the same functions with TAF1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MKRN2,PRDX3,FUS,P4HB,SIGIRR,CEBPG,LIN9,VPS25,CCNB3,FGFR4 |
| DNA binding | LMX1BB,TLX3B,FOXL1,NKX6.2,KMT2A,MSXD,ZMAT4,WRNIP1,ZSCAN18,ZBTB8A |
Interacting Protein
TAF1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF1A here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF1A.
TBP;C11orf57;C11orf57;SET;TAF1B;TAF1D;JMJD6;Wdr5;Kif22;Kif15;NAF1;VWA9
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