TAF13
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Official Full Name
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa -
Overview
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6. -
Synonyms
TAF13;TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa;TAF2K, TATA box binding protein (TBP) associated factor, RNA polymerase II, K, 18kD;transcription initiation factor TFIID subunit 13;TAFII18;MGC22425;TAF(II)18;TAF13 RNA polymerase II, TATA box binding protein (TBP) associated factor, 18kDa;TAF13_HUMAN;TAF2K;TAFII 18;TAFII-18;Transcription initiation factor TFIID 18 kDa subunit;OTTHUMP00000039343;OTTHUMP00000039344;transcription initiation factor TFIID 18 kD subunit;TATA box binding protein (TBP)-associated factor, RNA polymeras
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His&T7
- His
- Non
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TAF13-821H | Recombinant Human TAF13 Protein, GST-tagged | E.coli | Human | GST | 1-124 aa | |
| TAF13-1226H | Recombinant Human TAF13 protein, His & T7-tagged | E.coli | Human | His&T7 | Met1~Ser124 |
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| TAF13-1375Z | Recombinant Zebrafish TAF13 | Mammalian Cell | Zebrafish | His |
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| TAF13-1399C | Recombinant Chicken TAF13 | Mammalian Cell | Chicken | His |
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| TAF13-1275HCL | Recombinant Human TAF13 293 Cell Lysate | HEK293 | Human | Non |
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| Taf13-6277M | Recombinant Mouse Taf13 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| TAF13-6393H | Recombinant Human TAF13 Protein (Met1-Ser124), N-His tagged | E.coli | Human | His | Met1-Ser124 |
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| TAF13-826H | Recombinant Human TAF13 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
TAF13 involved in several pathways and played different roles in them. We selected most pathways TAF13 participated on our site, such as Basal transcription factors,Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Herpes simplex infection | IFNGR1,MAPK9,RNASEL,IFNPHI3,Casp3,Fasl,EIF2AK3,SRPK1A,NFKBIA,CLOCKB |
| Basal transcription factors | TAF7L,CCNH,TAF1,TAF2,GTF2F2B,TAF7,GTF2F2,GTF2A1L,GTF2H5,TBPL2 |
Protein Function
TAF13 has several biochemical functions, for example, DNA binding,protein C-terminus binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF13 itself. We selected most functions TAF13 had, and list some proteins which have the same functions with TAF13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein C-terminus binding | MAP3K7,DLG1,PPP2CA,CTGF,YEATS4,PCGF1,TOP2B,HPCAL4,SDCBP,TOP2A |
| protein binding | IL23R,PAWR,CLIC3,HIST1H3H,ADORA1,XIRP2,NFYA,RLN3,CCDC109A,CNO |
| transcription cofactor activity | MED12,BTG1,PHF21B,PTPN14,LDB2B,SUPT20H,ANKRA2,FAM48A,TADA2A,ZMYND11 |
| DNA binding | EPAS1,STAT5B,KAT6A,SMARCA5,GATA3,TOP2A,TSHZ1,SMAD9,HDGFRP2,SIX6 |
| transcription factor activity, sequence-specific DNA binding | EGR2,SOX4,NFAT5A,ZNF79,HIVEP2,TBX21,SNAPC2,HOXB7,IRF4A,Aff1 |
| protein heterodimerization activity | CEBPG,GRIN1,UBXN6,SUPT5H,TYR,AGTR1,TOP2B,HIST4H4,NFYB,Itgam&Itgb2 |
Interacting Protein
TAF13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF13 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF13.
MTUS2;TAF11;h3_peptide_2-18;MED26;CERK;NAF1;NLRP2
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