TAF10
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Official Full Name
Taf10p -
Overview
The basal transcription factor TFIID plays a central role in the regulation of gene expression in Eukaryota and is a large protein complex composed of TATA box-binding protein (TBP) and 14 kinds of TBP-associated factors (TAF). TFIID directly recognizes and binds to different kinds of core promoter elements that localize near the transcription initiation site and forms a scaffold for the other basal transcription factors to assemble. At the same time, it transmits transcriptional activation signal originating from transcription regulating factors to RNA polymerase II. Taf10p is one of the subunits of TFIID and in the case of budding yeast, it is composed of 206 amino acid residues (aa). Taf10p is also a subunit of histoneacetylase complex SAGA which is said to have an overlapping function with TFIID. This protein contains histone folds in its interior and forms dimers with Taf3p and Taf8p each. -
Synonyms
TAF10;Taf10p;TAF23;TAF25;NP_010451.1;YDR167W;Eukaryota;Fungi;Ascomycota;Saccharomycotina (true yeasts);Taphrinomycotina;Schizosaccharomycetes (fission yeasts);Basidiomycota;Agaricomycotina;Tremellomycetes;Pucciniomycotina;Microbotryomycetes
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
TAF10 involved in several pathways and played different roles in them. We selected most pathways TAF10 participated on our site, such as Basal transcription factors,Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Basal transcription factors | TAF7L,TAF6,ERCC2,MNAT1,GTF2F2A,GTF2H3,GTF2H5,GTF2IRD1,TAF11,ERCC3 |
| Herpes simplex infection | JAK2B,PILRA,SOCS3B,MCRS1,SRSF5,SRPK1,CASP8,RELA,EEF1D,TRP53 |
Protein Function
TAF10 has several biochemical functions, for example, RNA polymerase binding,enzyme binding,estrogen receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF10 itself. We selected most functions TAF10 had, and list some proteins which have the same functions with TAF10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to histone acetyltransferase activity | SUPT7L,TADA2B,TEX30,EPC1,TAF5L,ING3,TADA2A,SUPT3H,SAP130,KAT2A |
| estrogen receptor binding | HSD17B10,NCOA1,MMS19,PPID,ARRB1,NRIP1,LEF1,STRN,PADI2,MED1 |
| enzyme binding | MAPK14,MLL5,PTPLAD1,RAD9A,SLC12A3,YWHAE,GBP1,NOP14,HIST1H2AE,RPA2 |
| RNA polymerase binding | ANP32B,GSG1,PPIB,STOM,NEDD4,PKN2,RRN3,PHRF1,WDHD1,YTHDC2 |
| contributes_to transcription factor activity, sequence-specific DNA binding | FOXH1,SOX19A,NKX2,SMAD4,VDR,SOX19B,HNRNPAB,GATA4,VDRA,TAF12 |
| protein binding | FAM9A,USP2,FASTKD5,OTX2,ZFPM2,ROPN1,IL33,DDI1,CDKN3,EMG1 |
| transcription coactivator activity | BIRC2,MED1,VGLL1,APEX1,TADA1,MLL5,KLF7,NCOA3,YAP1,SMARCD1 |
| contributes_to protein binding | INTS10,MEF2A,INHA,CPSF3L,CRY1A,MSH2,ACVR2A,PAK1,TGFBR3,MSH6 |
Interacting Protein
TAF10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF10 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF10.
TBP;ATXN7;SETD7;KAT2B;BRCA1;FTL;h3_peptide_2-18;TAF4;MED26
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