TADA2L
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Official Full Name
TADA2A transcriptional adaptor 2A -
Overview
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined. -
Synonyms
ADA2;ADA2A;KL04P;hADA2;TADA2L;FLJ12705;transcriptional adapter 2-alpha;ADA2-like protein;OTTHUMP00000164062;OTTHUMP00000164063;transcriptional adaptor 2 alpha
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Involved Pathway
TADA2L involved in several pathways and played different roles in them. We selected most pathways TADA2L participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TADA2L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
TADA2L has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TADA2L itself. We selected most functions TADA2L had, and list some proteins which have the same functions with TADA2L. You can find most of the proteins on our site.
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Interacting Protein
TADA2L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TADA2L here. Most of them are supplied by our site. Hope this information will be useful for your research of TADA2L.
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