TACC1
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Official Full Name
transforming, acidic coiled-coil containing protein 1 -
Overview
This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Three transcript variants encoding different isoforms have been found for this gene. -
Synonyms
TACC1;transforming, acidic coiled-coil containing protein 1;transforming acidic coiled-coil-containing protein 1;taxin-1;gastric cancer antigen Ga55;Ga55;FLJ42304;KIAA1103;DKFZp686K18126
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TACC1-649HCL | Recombinant Human TACC1 lysate | HEK293 | Human | Non |
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| TACC1-128H | Recombinant Human TACC1 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| TACC1-4282H | Recombinant Human TACC1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Tacc1-6270M | Recombinant Mouse Tacc1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
TACC1 involved in several pathways and played different roles in them. We selected most pathways TACC1 participated on our site, such as Aurora A signaling,Aurora B signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TACC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Aurora A signaling | TACC3,NDEL1,OAZ1,TPX2,GADD45A,AURKAIP1,CENPA,TDRD7,AURKB |
| Aurora B signaling | NDC80,AURKB,CENPA,AURKC,DES,SEPT1,SGOL1,CDCA8,SMC4,KIF20A |
Protein Function
TACC1 has several biochemical functions, for example, protein binding,protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TACC1 itself. We selected most functions TACC1 had, and list some proteins which have the same functions with TACC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | XRCC4,NCOA2,TEKT3,ZFYVE21,TBCB,RAB3A,ATG12,SYNJ2,C4BPA,MOV10 |
| protein domain specific binding | ARHGEF4,ANGEL1,MLF1,NEFL,SKIL,NR0B1,PPP3R1,THRA,HIST1H4C,MRPL17 |
Interacting Protein
TACC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TACC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TACC1.
CKAP5;MEMO1;TDRD7;PRKRIR;STX5;SH2D4A
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References
- Line, A; Stengrevics, A; et al. Serological identification and expression analysis of gastric cancer-associated genes. BRITISH JOURNAL OF CANCER 86:1824-1830(2002).
