SYCP3
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Official Full Name
synaptonemal complex protein 3 -
Overview
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. -
Synonyms
SYCP3;synaptonemal complex protein 3;COR1;SCP3;SPGF4;MGC71888
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Cynomolgus
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- GST
- DDK
- Myc
- Avi
- Fc
Involved Pathway
SYCP3 involved in several pathways and played different roles in them. We selected most pathways SYCP3 participated on our site, such as Homologous recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with SYCP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Homologous recombination | SHFM1,RAD51L3,TOP3A,TOP3B,SSBP1,XRCC2,RAD54L,RPA1,RAD51D,MRE11A |
Protein Function
SYCP3 has several biochemical functions, for example, DNA binding,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SYCP3 itself. We selected most functions SYCP3 had, and list some proteins which have the same functions with SYCP3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | AXL,SNX6,TAP1,NKX2,HIST2H2L,INHA,SOX14,SNX5,H2AFB2,CHRNA3 |
| DNA binding | CSDC2,DHX9,HIST3H3,TCF3,RAD52,ZNF18,POLM,ZFP143,ZHX1,IRF2A |
Interacting Protein
SYCP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYCP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SYCP3.
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References
- Araya-Jaime, C; Serrano, EA; et al. Surface-spreading technique of meiotic cells and immunodetection of synaptonemal complex proteins in teleostean fishes. MOLECULAR CYTOGENETICS 8:-(2015).
- Sciurano, RB; Rahn, IM; et al. Dissociation of the X chromosome from the synaptonemal complex in the XY body of the rodent Galea musteloides. CHROMOSOME RESEARCH 21:753-763(2013).
