SULT1B1
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Official Full Name
sulfotransferase family, cytosolic, 1B, member 1 -
Overview
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of other SULT1 genes. -
Synonyms
SULT1B1;sulfotransferase family, cytosolic, 1B, member 1;sulfotransferase family cytosolic 1B member 1;ST1B2;SULT1B2;Dopa/tyrosine sulfotransferase;MGC13356;Sulfotransferase 1B1;Sulfotransferase 1B2;Thyroid hormone sulfotransferase;ST1B1
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Chicken
- E.coli
- Mammalian Cell
- Human
- HEK293
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Myc&SUMO
- His&Fc&Avi
Involved Pathway
SULT1B1 involved in several pathways and played different roles in them. We selected most pathways SULT1B1 participated on our site, such as Biological oxidations,Cytosolic sulfonation of small molecules,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SULT1B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Metabolism | GLRX,ACSF3,NDUFAF6,PCBD1,ACOT9.2,ARL2,CHAT,MED9,CD320,GGTLC1 |
Sulfation Biotransformation Reaction | SULT1C4,SULT4A1,SULT1C2 |
Phase II conjugation | UGT1B2,SULT1C2,AS3MT,SULT1C4,UGT1B7,UGT1B5,UGT1B4,SLC35B3,GLYATL2,SLC35D1A |
Cytosolic sulfonation of small molecules | SULT1C2,SULT1ST5,ABHD14B,Sult2a6,SLC35B3,SULT4A1,SLC35B2,SULT2ST2,Sult2a2,SLC26A2 |
Biological oxidations | ACY3.1,CES1,CYP1A1,FDXR,GLYATL2,ACSM1,CYP2AD3,CYP2B6,UGT1B2,SLC26A1 |
metapathway biotransformation | NAA30,CYP4V2,CYP2W1,HS3ST6,NAA50,PRKRA,GAL3ST3,NAT8,KCNAB1,KCNAB2 |
Protein Function
SULT1B1 has several biochemical functions, for example, aryl sulfotransferase activity,protein binding,sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SULT1B1 itself. We selected most functions SULT1B1 had, and list some proteins which have the same functions with SULT1B1. You can find most of the proteins on our site.
Function | Related Protein |
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sulfotransferase activity | SULT2ST2,SULT2ST3,SULT1ST7,HS6ST1,SULT1ST2,SULT1C2,HS3ST2,SULT1A1,Sult2a6,CHST10 |
aryl sulfotransferase activity | SULT1A3,SULT1A2,SULT1A1,SULT1A4,SULT1D1 |
protein binding | TERF1,HIST1H1C,GCA,PHF20L1,TRAPPC2L,SPTBN1,MLKL,PDE6D,TRIM23,ID3 |
Interacting Protein
SULT1B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SULT1B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SULT1B1.
SULT2B1;SDCBP;SULT2A1;POT1
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References
- Gong, JC; Gan, JP; et al. Identification of the Oxidative and Conjugative Enzymes Involved in the Biotransformation of Brivanib. DRUG METABOLISM AND DISPOSITION 40:219-226(2012).
- Xu, XJ; Patrakka, J; et al. Expression of Novel Podocyte-Associated Proteins sult1b1 and ankrd25. NEPHRON EXPERIMENTAL NEPHROLOGY 117:E39-E46(2011).