SUCLG2
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Official Full Name
succinate-CoA ligase, GDP-forming, beta subunit -
Overview
This gene encodes a GTP-specific beta subunit of succinyl-CoA synthetase. Succinyl-CoA synthetase catalyzes the reversible reaction involving the formation of succinyl-CoA and succinate. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 5 and 12. -
Synonyms
SUCLG2;succinate-CoA ligase, GDP-forming, beta subunit;succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial;EC 6.2.1.4;G BETA;GBETA;GTP specific succinyl-CoA synthetase beta subunit;GTP specific succinyl-CoA synthetase subunit beta;SCS betaG;Succinate CoA ligase GDP forming beta subunit;Succinate-Coenzyme A ligase, GDP-forming, beta subunit;Succinyl CoA ligase GDP forming beta chain mitochondrial;Succinyl CoA synthetase betaG chain;Succinyl-CoA synthetase beta-G chain;SCS-betaG;OTTHUMP00000213363;OTTHUMP00000213364;OTTHUMP00000213365;succinyl-CoA synthetase, beta-G chain;GTP-specific succinyl-CoA synthetase beta subunit;GTP-specific succinyl-CoA synthetase subunit beta;succinyl-CoA ligase, GDP-forming, beta chain, mitochondrial
Recombinant Proteins
- Human
- Chicken
- Mouse
- Rhesus macaque
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&SUMO
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SUCLG2-3043H | Recombinant Human SUCLG2, His-tagged | E.coli | Human | His | C-term-384aa | |
| SUCLG2-1293C | Recombinant Chicken SUCLG2 | Mammalian Cell | Chicken | His |
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| SUCLG2-16209M | Recombinant Mouse SUCLG2 Protein | Mammalian Cell | Mouse | His |
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| SUCLG2-4555R | Recombinant Rhesus monkey SUCLG2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| SUCLG2-1365HCL | Recombinant Human SUCLG2 293 Cell Lysate | HEK293 | Human | Non |
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| SUCLG2-3044H | Recombinant Human SUCLG2 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 49-423aa |
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| SUCLG2-4371R | Recombinant Rhesus Macaque SUCLG2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| SUCLG2-4371R-B | Recombinant Rhesus Macaque SUCLG2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| SUCLG2-8853M | Recombinant Mouse SUCLG2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SUCLG2-8853M-B | Recombinant Mouse SUCLG2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SUCLG2 involved in several pathways and played different roles in them. We selected most pathways SUCLG2 participated on our site, such as Citrate cycle (TCA cycle),Propanoate metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUCLG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Propanoate metabolism | LDHBB,HADHA,ACSS3,LDHA,ACSS1,ACADM,MCEE,DLDH,HADHAB,ACAT1 |
| Metabolic pathways | NDUFB3,ATP6V0C,SCP2A,AKR1C3,SPRA,FUT9,GLUD1B,FUT1,EXT1B,GUK1 |
| Carbon metabolism | CAT,ENO3,ACO2,PGAM1A,PGK1,HKDC1,RPE,HAO1,ALDH6A1,SHMT2 |
| Citrate cycle (TCA cycle) | MDH1,IDH3B,OGDHL,ACO1,PCK2,PDHB,PDHA1A,IDH1,ACLY,MDH2 |
Protein Function
SUCLG2 has several biochemical functions, for example, ATP binding,GTP binding,succinate-CoA ligase (GDP-forming) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SUCLG2 itself. We selected most functions SUCLG2 had, and list some proteins which have the same functions with SUCLG2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | ARL2,GPN3,THG1L,SEPT9,RAB22A,DIRAS1A,RABL6,RERGL,AK3,TUBB2A |
| ATP binding | VWA8,ATM,IARS,MKKS,KIF3CB,ATP1A3,ATP6V1BA,CKMT1,CDK16,ABCE1 |
| succinate-CoA ligase (GDP-forming) activity | SUCLG1 |
Interacting Protein
SUCLG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUCLG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUCLG2.
USP19;DMWD;SGCG;AK1;MYC;CD247;SIRT4
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