STX16

  • Official Full Name

    syntaxin 16
  • Overview

    This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants have been found for this gene. Read-through transcription also exists between this gene and the neighboring downstream aminopeptidase-like 1 (NPEPL1)gene.
  • Synonyms

    STX16;syntaxin 16;syntaxin-16;hsyn16;SYN16

Recombinant Proteins

  • Chicken
  • Rhesus macaque
  • Human
  • Mouse
  • Mammalian Cell
  • HEK293
  • E.coli expression system
  • HEK293T
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
STX16-1440C Recombinant Chicken STX16 Mammalian Cell Chicken His
STX16-4543R Recombinant Rhesus monkey STX16 Protein, His-tagged Mammalian Cell Rhesus macaque His
STX16-1380HCL Recombinant Human STX16 293 Cell Lysate HEK293 Human Non
RFL7578HF Recombinant Full Length Human Syntaxin-16(Stx16) Protein, His-Tagged E.coli expression system Human His Full L. Full Length (1-325)
STX16-1958H Recombinant Human STX16 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
STX16-4359R Recombinant Rhesus Macaque STX16 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
STX16-4359R-B Recombinant Rhesus Macaque STX16 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
Stx16-6204M Recombinant Mouse Stx16 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK

    Involved Pathway

    STX16 involved in several pathways and played different roles in them. We selected most pathways STX16 participated on our site, such as SNARE interactions in vesicular transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with STX16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    SNARE interactions in vesicular transport STX1A,STX6,STX1B,STX5A,SYBL1,BET1L,STX11A,SNAP23.2,GS15,VAMP8

    Protein Function

    STX16 has several biochemical functions, for example, SNAP receptor activity,protein binding,syntaxin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STX16 itself. We selected most functions STX16 had, and list some proteins which have the same functions with STX16. You can find most of the proteins on our site.

    Function Related Protein
    syntaxin binding SYT7,CPLX3,SNAP29,RAB11A,SYT5A,NAPB,ABL1,HECTD3,NAPAA,PTPN2
    SNAP receptor activity STX11A,STX5,VTI1B,SNAP47,STX5AL,STX2,STX1A,SEC22BA,STX4A,STX4
    protein binding NSMCE4A,DHPS,SGTB,CDC37,SPG11,OCLN,KLF11,ESD,SOX-2,MBNL1

    Interacting Protein

    STX16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STX16 here. Most of them are supplied by our site. Hope this information will be useful for your research of STX16.

    MEOX2;VAMP5;STX4;NAPB;PTPN12;rpoN;pi3p

    Resources

    Research Area

    Synaptic SNAREs

    References

    • Andersson, SA; Pedersen, MG; et al. Glucose-dependent docking and SNARE protein-mediated exocytosis in mouse pancreatic alpha-cell. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 462:443-454(2011).
    • Ng, EL; Wang, Y; et al. Rab22B's role in trans-Golgi network membrane dynamics. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 361:751-757(2007).

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