STARD6
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Official Full Name
StAR-related lipid transfer (START) domain containing 6 -
Overview
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g.,;SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and;SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and;uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute;regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid;STAR-related lipid transfer (START) domain, including STARD6 (Soccio et al., 2002 (PubMed 12011452)). -
Synonyms
STARD6;StAR-related lipid transfer (START) domain containing 6;START domain containing 6;stAR-related lipid transfer protein 6;STAR6_HUMAN;START domain-containing protein 6
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| STARD6-16104M | Recombinant Mouse STARD6 Protein | Mammalian Cell | Mouse | His |
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| STARD6-8783M | Recombinant Mouse STARD6 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| STARD6-8783M-B | Recombinant Mouse STARD6 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
STARD6 involved in several pathways and played different roles in them. We selected most pathways STARD6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with STARD6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
STARD6 has several biochemical functions, for example, cholesterol binding,lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STARD6 itself. We selected most functions STARD6 had, and list some proteins which have the same functions with STARD6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cholesterol binding | SYP,OSBPL5,CETP,APOA2,ANXA6,CYP11A1,ABCA1,OSBPL10,STAR,PTCH1 |
| lipid binding | OSBPL9,ESYT3,RBP7B,FFAR3,CYTH1,SNX10B,SEC14L3,APOL6,ACBD5A,APOEB |
Interacting Protein
STARD6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STARD6 here. Most of them are supplied by our site. Hope this information will be useful for your research of STARD6.
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References
- Chang, IY; Kim, JH; et al. Immunohistochemical detection of StarD6 in the rat nervous system. NEUROREPORT 18:1615-1619(2007).
- Rodriguez-Agudo, D; Ren, S; et al. Human StarD5, a cytosolic StAR-related lipid binding protein. JOURNAL OF LIPID RESEARCH 46:1615-1623(2005).
- Gomes, C; Oh, SD; et al. Expression of the putative sterol binding protein Stard6 gene is male germ cell specific. BIOLOGY OF REPRODUCTION 72:651-658(2005).
