ST8SIA5
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Official Full Name
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 -
Overview
The protein encoded by this gene is a type II membrane protein that may be present in the Golgi apparatus. The encoded protein, which is a member of glycosyltransferase family 29, may be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, and GT3 from GD1a, GT1b, GM1b, and GD3, respectively. -
Synonyms
ST8SIA5;ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5;sialyltransferase 8E (alpha 2, 8 polysialytransferase) , SIAT8E;alpha-2,8-sialyltransferase 8E;ST8Sia V;8-sialyltransferase 8E;Alpha-2;SIA8E_HUMAN;Sialyltransferase 8E;Sialytransferase St8Sia V;SIAT8-E;SIAT8E;ST8SiaV;sialyltransferase 8E (alpha-2, 8-polysialytransferase)
Recombinant Proteins
- Human
- Chicken
- Mouse
- Pan troglodytes
- Rhesus macaque
- Zebrafish
- Mus musculus
- E.coli
- Mammalian Cell
- E.Coli or Yeast
- E.coli expression system
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ST8SIA5-2984H | Recombinant Human ST8SIA5, His-tagged | E.coli | Human | His | 35-165aa | |
| ST8SIA5-1143C | Recombinant Chicken ST8SIA5 | Mammalian Cell | Chicken | His |
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| ST8SIA5-16082M | Recombinant Mouse ST8SIA5 Protein | Mammalian Cell | Mouse | His |
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| ST8SIA5-3321P | Recombinant Pan troglodytes (Chimpanzee) ST8SIA5, His-tagged | E.Coli or Yeast | Pan troglodytes | His | 376 |
|
| St8sia5-3322M | Recombinant Mouse St8sia5, His-tagged | E.Coli or Yeast | Mouse | His | 412 |
|
| ST8SIA5-4505R | Recombinant Rhesus monkey ST8SIA5 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| ST8SIA5-8006Z | Recombinant Zebrafish ST8SIA5 | Mammalian Cell | Zebrafish | His |
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| ST8SIA5-8007Z | Recombinant Zebrafish ST8SIA5 | Mammalian Cell | Zebrafish | His |
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| RFL11612MF | Recombinant Full Length Mouse Alpha-2,8-Sialyltransferase 8E(St8Sia5) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-412) |
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| RFL36408HF | Recombinant Full Length Human Alpha-2,8-Sialyltransferase 8E(St8Sia5) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-376) |
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| ST8SIA5-4321R | Recombinant Rhesus Macaque ST8SIA5 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| ST8SIA5-4321R-B | Recombinant Rhesus Macaque ST8SIA5 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| ST8SIA5-8768M | Recombinant Mouse ST8SIA5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ST8SIA5-8768M-B | Recombinant Mouse ST8SIA5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ST8SIA5 involved in several pathways and played different roles in them. We selected most pathways ST8SIA5 participated on our site, such as Glycosphingolipid biosynthesis - ganglio series,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ST8SIA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | PPT1,ADH6,AMDHD1,PNMT,ACO1,GGPS1,GBGT1L4,CYP3A65,ALP3,PLCG2 |
| Glycosphingolipid biosynthesis - ganglio series | HEXB,ST6GALNAC3,HEXA,B3GALT4,ST8SIA1,ST6GALNAC5,ST3GAL1,GLB1,ST3GAL5,SLC33A1 |
Protein Function
ST8SIA5 has several biochemical functions, for example, alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity,protein binding,sialyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ST8SIA5 itself. We selected most functions ST8SIA5 had, and list some proteins which have the same functions with ST8SIA5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity | ST8SIA3,ST8SIA1,ST8SIA2 |
| protein binding | RPGRIP1L,CREB1,MAD1L1,HNRNPF,TBC1D15,HTR3E,ZBTB6,BCCIP,RPL14,TMPO |
| sialyltransferase activity | ST6GALNAC5,ST3GAL3B,ST6GAL2B,ST8SIA3,ST8SIA1,ST6GALNAC2,ST6GALNAC1,ST3GAL3A,ST3GAL5L,ST6GALNAC4 |
Interacting Protein
ST8SIA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ST8SIA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ST8SIA5.
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References
- Lee, MTM; Chen, CH; et al. Genome-wide association study of bipolar I disorder in the Han Chinese population. MOLECULAR PSYCHIATRY 16:548-556(2011).
