SSX4B
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Official Full Name
synovial sarcoma, X breakpoint 4B -
Overview
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4B, represents the more centromeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene. -
Synonyms
SSX4B;synovial sarcoma, X breakpoint 4B;protein SSX4;OTTHUMT00000056510;Cancer/testis antigen 5.4;CT5.4;MGC119056;MGC12411;MGC169015;MGC169016;SSX4;SSX4A;Synovial sarcoma X breakpoint 4;Synovial sarcoma X breakpoint 4B
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Involved Pathway
SSX4B involved in several pathways and played different roles in them. We selected most pathways SSX4B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SSX4B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SSX4B has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SSX4B itself. We selected most functions SSX4B had, and list some proteins which have the same functions with SSX4B. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
SSX4B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SSX4B here. Most of them are supplied by our site. Hope this information will be useful for your research of SSX4B.
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