SPPL3

  • Official Full Name

    signal peptide peptidase-like 3
  • Overview

    Signal peptide peptidase 3, also known as UNQ1887, is a human gene.
  • Synonyms

    SPPL3;signal peptide peptidase-like 3;IMP-2;IMP2;Intramembrane protease 2;MDHV1887;MGC126674;MGC126676;MGC90402;Presenilin-like protein 4;PRO4332;PSL4;PSL4_HUMAN;signal peptide peptidase 3;SPP-like 3;Upregulated during skeletal muscle growth 3

Recombinant Proteins

  • Mouse
  • Zebrafish
  • Rhesus macaque
  • Mammalian Cells
  • HEK293
  • His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SPPL3-15923M Recombinant Mouse SPPL3 Protein Mammalian Cells Mouse His
SPPL3-2313Z Recombinant Zebrafish SPPL3 Mammalian Cells Zebrafish His
SPPL3-4445R Recombinant Rhesus monkey SPPL3 Protein, His-tagged Mammalian Cells Rhesus macaque His
SPPL3-4261R Recombinant Rhesus Macaque SPPL3 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
SPPL3-4261R-B Recombinant Rhesus Macaque SPPL3 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
SPPL3-8673M Recombinant Mouse SPPL3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SPPL3-8673M-B Recombinant Mouse SPPL3 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SPPL3 involved in several pathways and played different roles in them. We selected most pathways SPPL3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SPPL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    SPPL3 has several biochemical functions, for example, aspartic endopeptidase activity, intramembrane cleaving,aspartic-type endopeptidase activity,hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SPPL3 itself. We selected most functions SPPL3 had, and list some proteins which have the same functions with SPPL3. You can find most of the proteins on our site.

    Function Related Protein
    aspartic endopeptidase activity, intramembrane cleaving HM13,SPPL2B
    protein homodimerization activity STUB1,VEGFB,VIL1,QPRT,PRDM6,CTBP2A,MTPAP,MCL1B,SPPL2B,GAMT
    aspartic-type endopeptidase activity PIP,ATP6AP2,BACE2,REN,CTSE,Ren1,BACE1,CTSD,SPPL2,PSEN2
    hydrolase activity TMPRSS13A,ASAH1A,ABHD12B,DUSP28,ENPP5,PTPN11B,ATP6V0E2,STAMBPA,ACHE,PLCD3A
    protein binding PLK4,SMARCA5,C1QTNF9,VPS8,PLEKHO1,HLA-DOA,ADAM17,SPSB4,ACOT8,CEP350
    peptidase activity GM12824,REN2,C1RA,ASTL,ELANE,MALT1,DUB1,TMPRSS13B,NOTS,CASP9

    Interacting Protein

    SPPL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPPL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPPL3.

    Resources

    References

    • Lettau, M; Voss, M; et al. Differential protein-protein interactions of full length human FasL and FasL fragments generated by proteolysis. EXPERIMENTAL CELL RESEARCH 320:290-301(2014).

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