SPOP
-
Official Full Name
speckle-type POZ protein -
Synonyms
SPOP;speckle-type POZ protein;TEF2;HIB homolog 1;roadkill homolog 1
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- His
- T7
- Non
- His&Fc&Avi
- GST
- Flag
- Myc&DDK
Involved Pathway
SPOP involved in several pathways and played different roles in them. We selected most pathways SPOP participated on our site, such as Hedgehog on state,Hedgehog signaling events mediated by Gli proteins,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPOP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hedgehog on state | CDC73,KIF7,GAS8,EVC,BOC,SPOPL,DZIP1,IFT172,EFCAB7,CDON |
| Signaling by Hedgehog | IQCE,INTU,SCUBE2,GAS8,CDC73,IFT88,TTC21B,CDON,KIF7,TULP3 |
| mRNA processing | RBMS3,HNRNPH1L,HNRPL,FAM120B,SF3B2,CD2BP2,SF3A3,PRPF4B,PRPF8,RPL36A-HNRNPH2 |
| Hedgehog signaling events mediated by Gli proteins | MTSS1,SAP30,KIF3A,CSNK1G2,LGALS3,SAP18,SIN3B,IFT88,CSNK1G3 |
| Signal Transduction | OXGR1A.1,PTPRUB,USP15,GPR177,EDN3,LGR5,GPR161,ZNRF3,NCKIPSD,CRABP1B |
Protein Function
SPOP has several biochemical functions, for example, RNA polymerase II transcription factor binding,protein binding,ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPOP itself. We selected most functions SPOP had, and list some proteins which have the same functions with SPOP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin protein ligase binding | CUL2,SCAMP3,DERL1,LTBR,HIF1A,DAXX,CXCR4,YWHAE,SNX9,CUL3B |
| RNA polymerase II transcription factor binding | NFATC1,MEF2A,HCLS1,ZFPM1,TBX20,ZFPM2A,TBX6,ATF4,GATA6,MKX |
| protein binding | HBZ,NUDT1,ATF1,RNF144B,EDA,SEC61B,CCDC12,MX2,KIR2DL3,CUL4A |
Interacting Protein
SPOP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPOP here. Most of them are supplied by our site. Hope this information will be useful for your research of SPOP.
MYD88;DAXX;NCOA3;PTEN
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